Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues

Botanical pesticides are one of the sources of third-generation pesticides, which have received much attention at home and abroad in recent years due to their degradable and pollution-free advantages in nature. This article explored a concise approach toward synthesizing a series of novel L-pyroglut...

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Bibliographic Details
Published in:Frontiers in plant science 2022-12, Vol.13, p.1102411-1102411
Main Authors: Ai, Likun, Fu, Shiqi, Li, Yong, Zuo, Mei, Huang, Wen, Huang, Jian, Jin, Zhichao, Chen, Yang
Format: Article
Language:English
Subjects:
antifungal activity
benzenesulfonyl derivatives
botanical Pesticides
chiral hydroxyl
L-pyroglutamic acid
Plant Science
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Summary:Botanical pesticides are one of the sources of third-generation pesticides, which have received much attention at home and abroad in recent years due to their degradable and pollution-free advantages in nature. This article explored a concise approach toward synthesizing a series of novel L-pyroglutamic acid analogues from L-hydroxyproline. Furthermore, bioassay studies of these sulfonyl ester derivatives against , , , , and showed moderate antifungal activity. For instance, and provide potential lead agents for controlling because of their inhibitory activity.
ISSN:1664-462X
1664-462X
DOI:10.3389/fpls.2022.1102411