The effects of supervised aerobic training on dyslipidaemia among diabetic older patients

• Published in: BMC endocrine disorders 2024-10, Vol.24 (1), p.212-12, Article 212
• Main Authors: Alghadir, Ahmad H, Gabr, Sami A, Iqbal, Amir
• Format: Article
• Language: English
• Subjects: Adult; Aerobic exercise; Aerobic exercises; Aerobics; Aged; Biomarkers - blood; Blood glucose; Blood Glucose - analysis; Blood Glucose - metabolism; Blood levels; Blood pressure; Cardiorespiratory fitness; Cardiovascular disease; Cardiovascular diseases; Cardiovascular system; Care and treatment; Colorimetry; Complications and side effects; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - therapy; Diabetics; Dyslipidaemia; Dyslipidemia; Dyslipidemias; Dyslipidemias - blood; Dyslipidemias - therapy; Ethics; Exercise; Exercise Therapy - methods; Expenditures; Female; Fitness training programs; Glycated Hemoglobin - analysis; Glycated Hemoglobin - metabolism; Glycemic control; Health aspects; Hemoglobin; High density lipoprotein; hs-CRP; Humans; Hypertension; Inflammation; Insulin resistance; Life style; Lipids - blood; Low density lipoprotein; Male; Metabolic disorders; Middle Aged; Mortality; Physical activity; Physical fitness; Physical training; Prediabetic State - blood; Prediabetic State - therapy; Risk factors
• ISSN: 1472-6823; 1472-6823
• DOI: 10.1186/s12902-024-01745-8

Higher prevalence rates of diabetes and its complications have been reported among individuals with poor physical activity and a sedentary lifestyle. This study explored the influence of six months of moderate-intensity supervised aerobic training on the serum lipid profile, hs-CRP level, and variable-related correlations in prediabetic and type 2 diabetes patients (T2DM). The study was based on a two-arm parallel group pretest‒posttest comparative design. A total of 50 subjects who were diagnosed with diabetes for more than five years and aged 30-70 years were included in this study. The subjects were classified into two groups on the basis of their glycated haemoglobin (HbA1c%) values: Group 1 (patients with the prediabetes; HbA1c % ≤ 6.5, n = 25) and Group 2 (patients with the T2DM; HbA1c % ≥ 6.5, n = 25). Blood sugar, HbA1c %, insulin, lipid profile, and highly sensitive CRP (hs-CRP) were measured via colorimetric and immunoassay techniques at baseline and six months postintervention with moderate aerobic exercise. The results revealed that participation in moderate aerobic training interventions for six months resulted in a significant reduction in BMI, fasting blood sugar, glycosylated haemoglobin, hs-CRP, and lipid profile parameters such as T-Cholest, TG, and LDL-C as well as significant improvement in the level of insulin with a reduction in the values of HOMA-IR towards normal values in the patients with prediabetes (P