Advances in Editing Silkworms ( Bombyx mori ) Genome by Using the CRISPR-Cas System

CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) represents a powerful genome editing technology that revolutionized in a short period of time numerous natural sciences branches. Therefore, extraordinary progress was made in various fields, such as entomolog...

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Bibliographic Details
Published in:Insects (Basel, Switzerland) Switzerland), 2021-12, Vol.13 (1), p.28
Main Authors: Baci, Gabriela-Maria, Cucu, Alexandra-Antonia, Giurgiu, Alexandru-Ioan, Muscă, Adriana-Sebastiana, Bagameri, Lilla, Moise, Adela Ramona, Bobiș, Otilia, Rațiu, Attila Cristian, Dezmirean, Daniel Severus
Format: Article
Language:English
Subjects:
Adaptation
Bacteria
Bioreactors
Biosynthesis
Biotechnology
Bombyx mori
CRISPR
CRISPR-Cas
Entomology
Gene expression
Genetic engineering
Genetic modification
genome engineering
Genomes
Global economy
Impact analysis
insect biotechnology
Insects
Laboratories
Mutation
Organisms
Pest resistance
Plasmids
Proteins
Review
Sericulture
Silkworms
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Summary:CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) represents a powerful genome editing technology that revolutionized in a short period of time numerous natural sciences branches. Therefore, extraordinary progress was made in various fields, such as entomology or biotechnology. is one of the most important insects, not only for the sericulture industry, but for numerous scientific areas. The silkworms play a key role as a model organism, but also as a bioreactor for the recombinant protein production. Nowadays, the CRISPR-Cas genome editing system is frequently used in order to perform gene analyses, to increase the resistance against certain pathogens or as an imaging tool in . Here, we provide an overview of various studies that made use of CRISPR-Cas for genome editing, with a focus on emphasizing the high applicability of this system in entomology and biological sciences.
ISSN:2075-4450
2075-4450
DOI:10.3390/insects13010028