Effect of bispectral index monitoring on extubation time and analgesic consumption in abdominal surgery: a randomised clinical trial

• Published in: Swiss medical weekly 2012-10, Vol.142 (4142), p.w13689-w13689
• Main Authors: Persec, Jasminka, Persec, Zoran, Kopljar, Mario, Sojcic, Natasa, Husedzinovic, Ino
• Format: Article
• Language: English
• Subjects: abdominal surgery; Adjuvants, Anesthesia - administration & dosage; Adult; Aged; Aged, 80 and over; Airway Extubation; analgesia; Anesthesia - methods; Anesthesia Recovery Period; Anesthetics - administration & dosage; Anesthetics, Inhalation - administration & dosage; bispectral index monitoring; Blood Pressure; Consciousness Monitors; Drug Utilization; Electrocardiography; extubation; Female; Heart Rate; Humans; Male; Middle Aged; Monitoring, Intraoperative - methods; Time Factors
• ISSN: 1424-7860; 1424-3997
• DOI: 10.4414/smw.2012.13689

The aim of this study was to investigate the effect of bispectral index (BIS) monitoring on intra-operative anaesthesia consumption and extubation time. Randomised controlled study. The study included 45 patients undergoing major abdominal surgery under general anaesthesia in a six month period (February - July 2011), aged 18 years or older, and classified as ASA (American Society of Anaesthesiologists) physical status II or III. Patients were randomly assigned to receive BIS-guided anaesthesia or routine anaesthesia care as a non BIS-guided group. At the induction of anaesthesia, and during the operation the following parameters were continuously recorded: BIS level, heart rate (HR), systolic blood pressure (sBP), end-tidal CO2 (etCO2).Operation time and time to extubation were also recorded. On the first post-operative day all patients were visited and interviewed about intra-operative recall. BIS levels in the non BIS-guided group were significantly lower from 30 minutes further to the end of the operation, compared to the BIS-guided group (p