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Psychiatric implications of anti-seizure medications in epileptic population
Epilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is associated with a high occurrence of psychiatric comorbidities, which can significantly affect the quality of life of individuals affected. The aim of this study was to investig...
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| Published in: | BMC neurology 2024-05, Vol.24 (1), p.166-166, Article 166 |
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| creator | Khalid, Bushra Waqar, Zaid Khan, Soban Ali, Ijaz Afzal, Naheed Irfan, Anum Malik, Waleed Muhammad Adil, Malik Saddiqa, Amina Khalil, Maryam Munawar, Zeeshan |
| description | Epilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is associated with a high occurrence of psychiatric comorbidities, which can significantly affect the quality of life of individuals affected. The aim of this study was to investigate the association between antiseizure therapies and the likelihood of psychiatric comorbidities in individuals with epilepsy.
Data for this study was gathered from the Neurology referral center in Islamabad, Pakistan. A standardized questionnaire was utilized to gather data from 120 individuals diagnosed with epilepsy. The survey consisted of inquiries regarding the management of seizures, the utilization of anti-seizure medications, and the presence of psychiatric comorbidities. The data was analyzed using the Statistical Package for the Social Sciences (SPSS).
The findings indicated that individuals who were using multiple antiseizure medications had a notably higher likelihood of having psychiatric comorbidities in comparison to those who were on mono therapy (p = 0.010). suggests that patients with unsuccessful seizure control are more probable to have psychiatric comorbidities as compared to those with good seizure control (p = 0.029).
To conclude poor seizure control and poly therapy are associated with increased risk of psychiatric comorbidities. |
| doi_str_mv | 10.1186/s12883-024-03670-8 |
| format | article |
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Data for this study was gathered from the Neurology referral center in Islamabad, Pakistan. A standardized questionnaire was utilized to gather data from 120 individuals diagnosed with epilepsy. The survey consisted of inquiries regarding the management of seizures, the utilization of anti-seizure medications, and the presence of psychiatric comorbidities. The data was analyzed using the Statistical Package for the Social Sciences (SPSS).
The findings indicated that individuals who were using multiple antiseizure medications had a notably higher likelihood of having psychiatric comorbidities in comparison to those who were on mono therapy (p = 0.010). suggests that patients with unsuccessful seizure control are more probable to have psychiatric comorbidities as compared to those with good seizure control (p = 0.029).
To conclude poor seizure control and poly therapy are associated with increased risk of psychiatric comorbidities.</description><identifier>ISSN: 1471-2377</identifier><identifier>EISSN: 1471-2377</identifier><identifier>DOI: 10.1186/s12883-024-03670-8</identifier><identifier>PMID: 38773441</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adolescent ; Adult ; Analysis ; Anticonvulsants ; Anticonvulsants - therapeutic use ; Antiseizure medications ; Anxiety ; Brain research ; Care and treatment ; Comorbidity ; Complications and side effects ; Convulsions & seizures ; Disease ; Dosage and administration ; Drug therapy ; Drugs ; Epilepsy ; Epilepsy - drug therapy ; Epilepsy - epidemiology ; Epilepsy - psychology ; Female ; Health aspects ; Humans ; Investigations ; Levetiracetam ; Male ; Mental disorders ; Mental Disorders - drug therapy ; Mental Disorders - epidemiology ; Middle Aged ; MRI findings ; Nervous system diseases ; Pakistan - epidemiology ; Personality disorders ; Population ; Psychiatric comorbidities ; Psychological aspects ; Quality of life ; Questionnaires ; Seizures ; Seizures (Medicine) ; Surveys ; Surveys and Questionnaires ; Valproate ; Young Adult</subject><ispartof>BMC neurology, 2024-05, Vol.24 (1), p.166-166, Article 166</ispartof><rights>2024. The Author(s).</rights><rights>COPYRIGHT 2024 BioMed Central Ltd.</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c515t-423d1200d005fd9c711d6e270d0cfa0a40ec5ba1ab9c8fc00d83d9af5ae1dc33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11106872/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3066881235?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38773441$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khalid, Bushra</creatorcontrib><creatorcontrib>Waqar, Zaid</creatorcontrib><creatorcontrib>Khan, Soban</creatorcontrib><creatorcontrib>Ali, Ijaz</creatorcontrib><creatorcontrib>Afzal, Naheed</creatorcontrib><creatorcontrib>Irfan, Anum</creatorcontrib><creatorcontrib>Malik, Waleed</creatorcontrib><creatorcontrib>Muhammad Adil, Malik</creatorcontrib><creatorcontrib>Saddiqa, Amina</creatorcontrib><creatorcontrib>Khalil, Maryam</creatorcontrib><creatorcontrib>Munawar, Zeeshan</creatorcontrib><title>Psychiatric implications of anti-seizure medications in epileptic population</title><title>BMC neurology</title><addtitle>BMC Neurol</addtitle><description>Epilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is associated with a high occurrence of psychiatric comorbidities, which can significantly affect the quality of life of individuals affected. The aim of this study was to investigate the association between antiseizure therapies and the likelihood of psychiatric comorbidities in individuals with epilepsy.
Data for this study was gathered from the Neurology referral center in Islamabad, Pakistan. A standardized questionnaire was utilized to gather data from 120 individuals diagnosed with epilepsy. The survey consisted of inquiries regarding the management of seizures, the utilization of anti-seizure medications, and the presence of psychiatric comorbidities. The data was analyzed using the Statistical Package for the Social Sciences (SPSS).
The findings indicated that individuals who were using multiple antiseizure medications had a notably higher likelihood of having psychiatric comorbidities in comparison to those who were on mono therapy (p = 0.010). suggests that patients with unsuccessful seizure control are more probable to have psychiatric comorbidities as compared to those with good seizure control (p = 0.029).
To conclude poor seizure control and poly therapy are associated with increased risk of psychiatric comorbidities.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Analysis</subject><subject>Anticonvulsants</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Antiseizure medications</subject><subject>Anxiety</subject><subject>Brain research</subject><subject>Care and treatment</subject><subject>Comorbidity</subject><subject>Complications and side effects</subject><subject>Convulsions & seizures</subject><subject>Disease</subject><subject>Dosage and administration</subject><subject>Drug therapy</subject><subject>Drugs</subject><subject>Epilepsy</subject><subject>Epilepsy - drug therapy</subject><subject>Epilepsy - epidemiology</subject><subject>Epilepsy - psychology</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Investigations</subject><subject>Levetiracetam</subject><subject>Male</subject><subject>Mental disorders</subject><subject>Mental Disorders - drug therapy</subject><subject>Mental Disorders - epidemiology</subject><subject>Middle Aged</subject><subject>MRI findings</subject><subject>Nervous system diseases</subject><subject>Pakistan - epidemiology</subject><subject>Personality disorders</subject><subject>Population</subject><subject>Psychiatric comorbidities</subject><subject>Psychological aspects</subject><subject>Quality of life</subject><subject>Questionnaires</subject><subject>Seizures</subject><subject>Seizures (Medicine)</subject><subject>Surveys</subject><subject>Surveys and Questionnaires</subject><subject>Valproate</subject><subject>Young Adult</subject><issn>1471-2377</issn><issn>1471-2377</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkktv1DAUhSMEoqXwB1igkdiwSfGNn1mhquJRaSRYdG_d-DH1KImDnSC1vx53pgydqvLClu85n33tU1XvgZwDKPE5Q6MUrUnDakKFJLV6UZ0Ck1A3VMqXj9Yn1Zuct4SAVAxeVydUSUkZg9Nq_SvfmpuAcwpmFYapDwbnEMe8in6F4xzq7MLdktxqcPZQC-PKTaF301xcU5yWfld4W73y2Gf37mE-q66_fb2-_FGvf36_urxY14YDn2vWUAsNIZYQ7m1rJIAVrpFlw3gkyIgzvEPArjXKmyJU1LboOTqwhtKz6mqPtRG3ekphwHSrIwa924hpozGVm_VOK4VAmUQBzDPWcWWJ4Nhy1XasBcEL68ueNS1d6dC4cU7YH0GPK2O40Zv4RwMAEUo2hfDpgZDi78XlWQ8hG9f3OLq4ZE0JV4IKBaJIPz6RbuOSxvJURSWEUtBQ_l-1wdJBGH0sB5t7qL6QLZOC8R3r_BlVGdYNwcTR-fI_x4ZmbzAp5pycPzQJRN_nSe_zpEue9C5PWhXTh8fPc7D8CxD9C19TxTk</recordid><startdate>20240521</startdate><enddate>20240521</enddate><creator>Khalid, Bushra</creator><creator>Waqar, Zaid</creator><creator>Khan, Soban</creator><creator>Ali, Ijaz</creator><creator>Afzal, Naheed</creator><creator>Irfan, Anum</creator><creator>Malik, Waleed</creator><creator>Muhammad Adil, Malik</creator><creator>Saddiqa, Amina</creator><creator>Khalil, Maryam</creator><creator>Munawar, Zeeshan</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240521</creationdate><title>Psychiatric implications of anti-seizure medications in epileptic population</title><author>Khalid, Bushra ; Waqar, Zaid ; Khan, Soban ; Ali, Ijaz ; Afzal, Naheed ; Irfan, Anum ; Malik, Waleed ; Muhammad Adil, Malik ; Saddiqa, Amina ; Khalil, Maryam ; Munawar, Zeeshan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c515t-423d1200d005fd9c711d6e270d0cfa0a40ec5ba1ab9c8fc00d83d9af5ae1dc33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Analysis</topic><topic>Anticonvulsants</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Antiseizure medications</topic><topic>Anxiety</topic><topic>Brain research</topic><topic>Care and treatment</topic><topic>Comorbidity</topic><topic>Complications and side effects</topic><topic>Convulsions & seizures</topic><topic>Disease</topic><topic>Dosage and administration</topic><topic>Drug therapy</topic><topic>Drugs</topic><topic>Epilepsy</topic><topic>Epilepsy - drug therapy</topic><topic>Epilepsy - epidemiology</topic><topic>Epilepsy - psychology</topic><topic>Female</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Investigations</topic><topic>Levetiracetam</topic><topic>Male</topic><topic>Mental disorders</topic><topic>Mental Disorders - drug therapy</topic><topic>Mental Disorders - epidemiology</topic><topic>Middle Aged</topic><topic>MRI findings</topic><topic>Nervous system diseases</topic><topic>Pakistan - epidemiology</topic><topic>Personality disorders</topic><topic>Population</topic><topic>Psychiatric comorbidities</topic><topic>Psychological aspects</topic><topic>Quality of life</topic><topic>Questionnaires</topic><topic>Seizures</topic><topic>Seizures (Medicine)</topic><topic>Surveys</topic><topic>Surveys and Questionnaires</topic><topic>Valproate</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khalid, Bushra</creatorcontrib><creatorcontrib>Waqar, Zaid</creatorcontrib><creatorcontrib>Khan, Soban</creatorcontrib><creatorcontrib>Ali, Ijaz</creatorcontrib><creatorcontrib>Afzal, Naheed</creatorcontrib><creatorcontrib>Irfan, Anum</creatorcontrib><creatorcontrib>Malik, Waleed</creatorcontrib><creatorcontrib>Muhammad Adil, Malik</creatorcontrib><creatorcontrib>Saddiqa, Amina</creatorcontrib><creatorcontrib>Khalil, Maryam</creatorcontrib><creatorcontrib>Munawar, Zeeshan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Publicly Available Content database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>BMC neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khalid, Bushra</au><au>Waqar, Zaid</au><au>Khan, Soban</au><au>Ali, Ijaz</au><au>Afzal, Naheed</au><au>Irfan, Anum</au><au>Malik, Waleed</au><au>Muhammad Adil, Malik</au><au>Saddiqa, Amina</au><au>Khalil, Maryam</au><au>Munawar, Zeeshan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychiatric implications of anti-seizure medications in epileptic population</atitle><jtitle>BMC neurology</jtitle><addtitle>BMC Neurol</addtitle><date>2024-05-21</date><risdate>2024</risdate><volume>24</volume><issue>1</issue><spage>166</spage><epage>166</epage><pages>166-166</pages><artnum>166</artnum><issn>1471-2377</issn><eissn>1471-2377</eissn><abstract>Epilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is associated with a high occurrence of psychiatric comorbidities, which can significantly affect the quality of life of individuals affected. The aim of this study was to investigate the association between antiseizure therapies and the likelihood of psychiatric comorbidities in individuals with epilepsy.
Data for this study was gathered from the Neurology referral center in Islamabad, Pakistan. A standardized questionnaire was utilized to gather data from 120 individuals diagnosed with epilepsy. The survey consisted of inquiries regarding the management of seizures, the utilization of anti-seizure medications, and the presence of psychiatric comorbidities. The data was analyzed using the Statistical Package for the Social Sciences (SPSS).
The findings indicated that individuals who were using multiple antiseizure medications had a notably higher likelihood of having psychiatric comorbidities in comparison to those who were on mono therapy (p = 0.010). suggests that patients with unsuccessful seizure control are more probable to have psychiatric comorbidities as compared to those with good seizure control (p = 0.029).
To conclude poor seizure control and poly therapy are associated with increased risk of psychiatric comorbidities.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38773441</pmid><doi>10.1186/s12883-024-03670-8</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | BMC neurology, 2024-05, Vol.24 (1), p.166-166, Article 166 |
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| subjects | Adolescent Adult Analysis Anticonvulsants Anticonvulsants - therapeutic use Antiseizure medications Anxiety Brain research Care and treatment Comorbidity Complications and side effects Convulsions & seizures Disease Dosage and administration Drug therapy Drugs Epilepsy Epilepsy - drug therapy Epilepsy - epidemiology Epilepsy - psychology Female Health aspects Humans Investigations Levetiracetam Male Mental disorders Mental Disorders - drug therapy Mental Disorders - epidemiology Middle Aged MRI findings Nervous system diseases Pakistan - epidemiology Personality disorders Population Psychiatric comorbidities Psychological aspects Quality of life Questionnaires Seizures Seizures (Medicine) Surveys Surveys and Questionnaires Valproate Young Adult |
| title | Psychiatric implications of anti-seizure medications in epileptic population |
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