Can Modification with Urethane Derivatives or the Addition of an Anti-Hydrolysis Agent Influence the Hydrolytic Stability of Resin Dental Composite?

• Published in: International journal of molecular sciences 2023-02, Vol.24 (5), p.4336
• Main Authors: Szczesio-Wlodarczyk, Agata, Barszczewska-Rybarek, Izabela M, Chrószcz-Porębska, Marta W, Kopacz, Karolina, Sokolowski, Jerzy, Bociong, Kinga
• Format: Article
• Language: English
• Subjects: Additives; Aging; Aging methods; anti-hydrolysis agent; Biocompatibility; Bisphenol A; Bisphenol A-Glycidyl Methacrylate; Carbodiimide; clinical performance; Composite materials; Composite Resins; Dental cement; dental composites; Dental materials; Dental restorative materials; Diisocyanates; Ethyl carbamate; Flexural strength; Hardness; Hydrolysis; hydrolytic stability; Hypotheses; Isocyanates; Materials Testing; Mechanical properties; Methacrylates; Polyethylene Glycols; Polymerization; Polymers; Polymethacrylic Acids; Polyurethanes; Reagents; Service life; Sodium Hydroxide; Stability analysis; Tensile strength; Triethylene glycol dimethacrylate; urethane-dimethacrylate derivatives; Urethanes; Water
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms24054336

Due to the questionable durability of dental restorations, there is a need to increase the lifetime of composite restoration. The present study used diethylene glycol monomethacrylate/4,4'-methylenebis(cyclohexyl isocyanate) (DEGMMA/CHMDI), diethylene glycol monomethacrylate/isophorone diisocyanate (DEGMMA/IPDI) monomers, and bis(2,6-diisopropylphenyl)carbodiimide (CHINOX SA-1) as modifiers of a polymer matrix (40 wt% urethane dimethacrylate (UDMA), 40 wt% bisphenol A ethoxylateddimethacrylate (bis-EMA), and 20 wt% triethyleneglycol dimethacrylate (TEGDMA)). Flexural strength (FS), diametral tensile strength (DTS), hardness (HV), sorption, and solubility were determined. To assess hydrolytic stability, the materials were tested before and after two aging methods (I-7500 cycles, 5 °C and 55 °C, water and 7 days, 60 °C, 0.1 M NaOH; II-5 days, 55 °C, water and 7 days, 60 °C, 0.1 M NaOH). The aging protocol resulted in no noticeable change (median values were the same as or higher than the control value) or a decrease in the DTS value from 4 to 28%, and a decrease in the FS value by 2 to 14%. The hardness values after aging were more than 60% lower than those of the controls. The used additives did not improve the initial (control) properties of the composite material. The addition of CHINOX SA-1 improved the hydrolytic stability of composites based on UDMA/bis-EMA/TEGDMA monomers, which could potentially extend the service life of the modified material. Extended studies are needed to confirm the possible use of CHINOX SA-1 as an antihydrolysis agent in dental composites.