A newly proposed heatstroke-induced coagulopathy score in patients with heat illness: A multicenter retrospective study in China

In patients with heatstroke, disseminated intravascular coagulation (DIC) is associated with greater risk of in-hospital mortality. However, time-consuming assays or a complex diagnostic system may delay immediate treatment. Therefore, the present study proposes a new heatstroke-induced coagulopathy...

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Bibliographic Details
Published in:Chinese journal of traumatology 2024-03, Vol.27 (2), p.83-90
Main Authors: Lin, Qing-Wei, Zhong, Lin-Cui, He, Long-Ping, Zeng, Qing-Bo, Zhang, Wei, Song, Qing, Song, Jing-Chun
Format: Article
Language:English
Subjects:
Adolescent
Blood Coagulation Disorders - diagnosis
Blood Coagulation Disorders - epidemiology
Blood Coagulation Disorders - etiology
Coagulation disorders
Diagnosis
Disseminated intravascular coagulation
Disseminated Intravascular Coagulation - diagnosis
Disseminated Intravascular Coagulation - epidemiology
Disseminated Intravascular Coagulation - etiology
Heat illness
Heat Stroke - complications
Heatstroke
Humans
Original
Retrospective Studies
Thrombosis
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Summary:In patients with heatstroke, disseminated intravascular coagulation (DIC) is associated with greater risk of in-hospital mortality. However, time-consuming assays or a complex diagnostic system may delay immediate treatment. Therefore, the present study proposes a new heatstroke-induced coagulopathy (HIC) score in patients with heat illness as an early warning indicator for DIC. This retrospective study enrolled patients with heat illness in 24 Chinese hospitals from March 2021 to May 2022. Patients under 18 years old, with a congenital clotting disorder or liver disease, or using anticoagulants were excluded. Data were collected on demographic characteristics, routine blood tests, conventional coagulation assays and biochemical indexes. The risk factors related to coagulation function in heatstroke were identified by regression analysis, and used to construct a scoring system for HIC. The data of patients who met the diagnostic criteria for HIC and International Society on Thrombosis and Haemostasis defined-DIC were analyzed. All statistical analyses were performed using SPSS 26.0. The final analysis included 302 patients with heat illness, of whom 131 (43.4%) suffered from heatstroke, including 7 death (5.3%). Core temperature (OR = 1.681, 95% CI 1.291 − 2.189, p 
ISSN:1008-1275
1008-1275
DOI:10.1016/j.cjtee.2023.08.001