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Low-frequency sound affects active micromechanics in the human inner ear
Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (less than 250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness...
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Published in: | Royal Society open science 2014-10, Vol.1 (2), p.140166-140166 |
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description | Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (less than 250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea which are driven very inadequately at low frequencies. To assess the impact of low-frequency (LF) sound, we exploited a by-product of the active amplification of sound outer hair cells (OHCs) perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, LF sounds significantly affects OHCs: a 90 s, 80 dB(A) LF sound induced slow, concordant and positively correlated frequency and level oscillations of spontaneous otoacoustic emissions that lasted for about 2 min after LF sound offset. LF sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing. |
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Soc. open sci</addtitle><addtitle>R. Soc. open sci</addtitle><description>Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (less than 250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea which are driven very inadequately at low frequencies. To assess the impact of low-frequency (LF) sound, we exploited a by-product of the active amplification of sound outer hair cells (OHCs) perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. 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LF sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.</description><subject>Cochlea</subject><subject>Low-Frequency Sound</subject><subject>Noise-Induced Hearing Loss</subject><subject>Spontaneous Otoacoustic Emissions</subject><issn>2054-5703</issn><issn>2054-5703</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9UV2LEzEUHURxl3WffJd5FKRrMvl-EXRRu1BY1voFPlwymWSb2pnUZKZaf72pU0tXRAhJbu6559zcUxSPMbrASMnnMYV0gSnCnN8rTivE6IQJRO4f3U-K85SWCCHMEBFcPCxOKo44ZYSfFtNZ-D5x0X4bbGe2ZQpD15TaOWv6VGrT-40tW29iaK1Z6M6bVPqu7Be2XAyt7nLQ2VhaHR8VD5xeJXu-P8-KD29ev7-cTmbXb68uX84mhmPU73bNqkbVzkhuBK543QjCiJFWIlYrbBrHnVO6tlxzTioiEc15oRzlTUXJWXE18jZBL2EdfavjFoL28PshxFvQsfdmZUEqLBrUME2MoMgo7eoaNVmJSYLrWmWuFyPXeqhb2xjb9VGv7pDezXR-AbdhA5RSKRXPBE_3BDHkCaYeWp-MXa10Z8OQAHMplOKY4Qx9NkLzLFOK1h1kMIKdlbCzEkYrM_rJcWcH7B_jMuDLCIhhm8cdjLf9FpZhiF0O4d38er7BvgKUv4pYXhX89Ou9BviUBgvVseRf8uh_7P_ueDKW-NTbH4eGdfwKXBDB4KOkMJ3ffK4-sRt4RX4BZ3faBA</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Kugler, Kathrin</creator><creator>Wiegrebe, Lutz</creator><creator>Grothe, Benedikt</creator><creator>Kössl, Manfred</creator><creator>Gürkov, Robert</creator><creator>Krause, Eike</creator><creator>Drexl, Markus</creator><general>The Royal Society</general><general>The Royal Society Publishing</general><scope>BSCLL</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20141001</creationdate><title>Low-frequency sound affects active micromechanics in the human inner ear</title><author>Kugler, Kathrin ; Wiegrebe, Lutz ; Grothe, Benedikt ; Kössl, Manfred ; Gürkov, Robert ; Krause, Eike ; Drexl, Markus</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c610t-c61a52d9bfc86c7126bd7353c8e805b91cdf6ff9abe6a6632380435379f46d243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Cochlea</topic><topic>Low-Frequency Sound</topic><topic>Noise-Induced Hearing Loss</topic><topic>Spontaneous Otoacoustic Emissions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kugler, Kathrin</creatorcontrib><creatorcontrib>Wiegrebe, Lutz</creatorcontrib><creatorcontrib>Grothe, Benedikt</creatorcontrib><creatorcontrib>Kössl, Manfred</creatorcontrib><creatorcontrib>Gürkov, Robert</creatorcontrib><creatorcontrib>Krause, Eike</creatorcontrib><creatorcontrib>Drexl, Markus</creatorcontrib><collection>Istex</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Royal Society open science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kugler, Kathrin</au><au>Wiegrebe, Lutz</au><au>Grothe, Benedikt</au><au>Kössl, Manfred</au><au>Gürkov, Robert</au><au>Krause, Eike</au><au>Drexl, Markus</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low-frequency sound affects active micromechanics in the human inner ear</atitle><jtitle>Royal Society open science</jtitle><stitle>R. 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subjects | Cochlea Low-Frequency Sound Noise-Induced Hearing Loss Spontaneous Otoacoustic Emissions |
title | Low-frequency sound affects active micromechanics in the human inner ear |
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