Simultaneous meningioma and brain metastasis from renal cell carcinoma - a rare presentation. Case report

• Published in: São Paulo medical journal 2017-05, Vol.135 (3), p.296-301
• Main Authors: Campos Paiva, Aline Lariessy, Vitorino Araujo, João Luiz, Ferraz, Vinícius Ricieri, Esteves Veiga, José Carlos
• Format: Article
• Language: English
• Subjects: Brain neoplasms; Carcinoma, renal cell; Carcinoma, Renal Cell - secondary; Cerebral ventricle neoplasms; Cerebral Ventricle Neoplasms - diagnostic imaging; Cerebral Ventricle Neoplasms - secondary; Cerebral Ventricle Neoplasms - surgery; Humans; Immunohistochemistry; Kidney Neoplasms - pathology; Magnetic Resonance Imaging; Male; MEDICINE, GENERAL & INTERNAL; Meningeal Neoplasms - diagnostic imaging; Meningeal Neoplasms - secondary; Meningeal Neoplasms - surgery; Meningioma; Meningioma - diagnostic imaging; Meningioma - secondary; Meningioma - surgery; Middle Aged; Neoplasm metastasis; Rare Diseases; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 1516-3180; 1806-9460; 1806-9460
• DOI: 10.1590/1516-3180.2016.016228102016

Brain metastases are the most common tumors of the central nervous system. Because of their high frequency, they may be associated with rare situations. Among these are tumor-to-tumor metastasis and an even a rarer situation called simultaneous brain tumors, which are more related to primary tumors of the reproductive and endocrine systems. A 56-year-old male patient with a history of renal cell carcinoma (which had previously been resected) presented with a ventricular lesion (suggestive of metastatic origin) and simultaneous olfactory groove lesion (probably a meningioma). First, only the ventricular lesion was dealt with, but after a year, the meningothelial lesion increased and an occipital lesion appeared. Therefore, both of these were resected in a single operation. All the procedures were performed by the same neurosurgeon. The patient evolved without neurological deficits during the postoperative period. After these two interventions, the patient remained well and was referred for adjuvant treatment. This study provides the first description of an association between these two tumors. Brain metastases may be associated with several lesions, and rare presentations such as simultaneity with meningioma should alert neurosurgeons to provide the best oncological treatment.