The Possible Clinical Predictors of Fatigue in Parkinson’s Disease: A Study of 135 Patients as Part of International Nonmotor Scale Validation Project

Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured...

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Bibliographic Details
Published in:Parkinson's disease 2011-01, Vol.2011 (2011), p.20-26
Main Authors: Barone, P., Stocchi, Fabrizio, Antonini, Angelo, Chaudhuri, K. Ray, Martin, Anne, Kaluarachchi, T. K., Schartau, P. E. S., Gage, Heather M., Martinez-Martin, Pablo, Logishetty, Kartik, Metta, Vinod, Odin, Per
Format: Article
Language:English
Subjects:
Clinical Study
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Summary:Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.
ISSN:2042-0080
2090-8083
2042-0080
DOI:10.4061/2011/125271