False Positive Tramadol Urine Testing in Patients Taking Fexofenadine: A Tale of Two Consecutive Cases

Urine drug screen immunoassays have been widely used as point-of-care testing for detection of various drug classes in substance use disorders. However, these immunoassays frequently result in false positive results. We report two patients that used 180 mg daily dose of fexofenadine hydrochloride fo...

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Bibliographic Details
Published in:Case reports in psychiatry 2023-01, Vol.2023, p.4370648-4
Main Authors: Yousuf, Suhair Mohammed, Alater, Ahmad Maaen, Alabdulla, Majid, Osman, Mugtaba
Format: Article
Language:English
Subjects:
Alcohol
Analysis
Case Report
Case reports
Chromatography
Dermatologic agents
Dermatology
Drug testing
Formulae, receipts, prescriptions
Histamine
Immunoassay
Laboratories
Mass spectrometry
Patients
Psychotropic drugs
Rehabilitation
Scientific imaging
Skin care products
Substance abuse
Substance abuse treatment
Tramadol
Urine
Urticaria
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Summary:Urine drug screen immunoassays have been widely used as point-of-care testing for detection of various drug classes in substance use disorders. However, these immunoassays frequently result in false positive results. We report two patients that used 180 mg daily dose of fexofenadine hydrochloride for treatment of skin allergy and, falsely, tested positive for use of tramadol during urine drug screening. We recommend caution when interpreting positive tramadol urine screening among patients on fexofenadine treatment.
ISSN:2090-682X
2090-6838
DOI:10.1155/2023/4370648