The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms

The research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu2+-doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu2+-doped nanohydroxyapatite, respectively. Their potential antimicrobial activity was investig...

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Published in:Nanomaterials (Basel, Switzerland) Switzerland), 2020-10, Vol.10 (10), p.1997
Main Authors: Zakrzewski, Wojciech, Dobrzynski, Maciej, Nowicka, Joanna, Pajaczkowska, Magdalena, Szymonowicz, Maria, Targonska, Sara, Sobierajska, Paulina, Wiglusz, Katarzyna, Dobrzynski, Wojciech, Lubojanski, Adam, Fedorowicz, Sebastian, Rybak, Zbigniew, Wiglusz, Rafal J.
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Biological activity
Biomedical materials
Bones
Copper
Crystal lattices
Crystal structure
Cu2+ ions
Cytotoxicity
Electron microscopy
Fourier transforms
Hydroxyapatite
Microorganisms
Minimum inhibitory concentration
Morphology
Nanoparticles
Olive oil
Orthopedics
ozonated olive oil
Scanning electron microscopy
Spectrophotometry
Statistical methods
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container_title Nanomaterials (Basel, Switzerland)
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creator Zakrzewski, Wojciech
Dobrzynski, Maciej
Nowicka, Joanna
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Szymonowicz, Maria
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Sobierajska, Paulina
Wiglusz, Katarzyna
Dobrzynski, Wojciech
Lubojanski, Adam
Fedorowicz, Sebastian
Rybak, Zbigniew
Wiglusz, Rafal J.
description The research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu2+-doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu2+-doped nanohydroxyapatite, respectively. Their potential antimicrobial activity was investigated against Streptococcus mutans, Lactobacillus rhamnosus, and Candida albicans. Among all tested materials, the highest efficacy was observed in terms of ozonated olive oil. The studies were performed using an Ultraviolet–Visible spectrophotometry (UV-Vis), electron microscopy, and statistical methods, by determining the value of Colony-Forming Units (CFU/mL) and Minimal Inhibitory Concentration (MIC).
doi_str_mv 10.3390/nano10101997
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subjects Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Biological activity
Biomedical materials
Bones
Copper
Crystal lattices
Crystal structure
Cu2+ ions
Cytotoxicity
Electron microscopy
Fourier transforms
Hydroxyapatite
Microorganisms
Minimum inhibitory concentration
Morphology
Nanoparticles
Olive oil
Orthopedics
ozonated olive oil
Scanning electron microscopy
Spectrophotometry
Statistical methods
title The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms
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