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Comment on: “Pitfalls in the measurement of muscle mass: a need for a reference standard” by Buckinx et al

[...]Delmonico et al. compared changes in muscle size in older adults in response to a 3‐month resistance exercise training programme and only found a moderate association (r = 0.53) between DXA and full‐thigh multi‐slice CT‐derived measures of change in muscle size. In support, Hansen et al. also f...

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Bibliographic Details
Published in:Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2018-12, Vol.9 (7), p.1269-1271
Main Authors: Clark, Brian C., Tavoian, Dallin, Goodpaster, Bret H., Cawthon, Peggy M., Hansen, Ross D., Manini, Todd M.
Format: Article
Language:English
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Summary:[...]Delmonico et al. compared changes in muscle size in older adults in response to a 3‐month resistance exercise training programme and only found a moderate association (r = 0.53) between DXA and full‐thigh multi‐slice CT‐derived measures of change in muscle size. In support, Hansen et al. also found a moderate association between mid‐thigh CT single‐slice CSA and DXA LSTM from a comparable region of interest (r = 0.51) in older adults after surgical repair of the femoral neck. Data of this nature raise concern about the working group's recommendation that DXA be considered the standard for assessing muscle mass, particularly when one considers that their recommendation was within the broader context of monitoring the change in muscle mass in healthy adults, athletes, and in those managing chronic diseases.
ISSN:2190-5991
2190-6009
DOI:10.1002/jcsm.12372