A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves’ Disease with Methimazole

We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves’ disease with methimazole. The patient’s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and...

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Bibliographic Details
Published in:Case reports in endocrinology 2013-01, Vol.2013 (2013), p.1-4
Main Authors: Miyashita, Kazuyuki, Yasuda, Tetsuyuki, Kaneto, Hideaki, Kuroda, Akio, Kitamura, Tetsuhiro, Otsuki, Michio, Okamoto, Yasuyuki, Hamada, Noboru, Matsuhisa, Munehide, Shimomura, Iichiro
Format: Article
Language:English
Subjects:
Bone density
Case Report
Disease
Metabolic disorders
Older people
Vitamin D
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Summary:We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves’ disease with methimazole. The patient’s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and inadequate exposure to sunlight in addition to the resolution of hyperthyroidism. Vitamin D deficiency is increasing worldwide, and it has been more recently shown to relate to the pathogenesis of Graves’ disease. However, vitamin D deficiency as a cause of hypocalcemia has received little attention. Taken together, this case suggests that we should take more care in calcium kinetics and vitamin D status during treatment for Graves’ disease with antithyroid drugs.
ISSN:2090-6501
2090-651X
DOI:10.1155/2013/512671