An overview of the management of osteoporosis in the aging female population

Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the...

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Bibliographic Details
Published in:Women's Health 2023-01, Vol.19, p.17455057231176655-17455057231176655
Main Authors: Amin, Usman, McPartland, Aoife, O’Sullivan, Miriam, Silke, Carmel
Format: Article
Language:English
Subjects:
Aging
Bisphosphonates
Bone Density
Bone Density Conservation Agents - pharmacology
Bone Density Conservation Agents - therapeutic use
Bone mineral density
Cardiovascular and Metabolic Bone Health in Aging Women
Diphosphonates - pharmacology
Diphosphonates - therapeutic use
Female
Fractures
Health services
Humans
Monoclonal antibodies
Morbidity
Older people
Osteoporosis
Osteoporosis - drug therapy
Osteoporosis - etiology
Osteoporosis, Postmenopausal - complications
Osteoporosis, Postmenopausal - drug therapy
Osteoporotic Fractures - complications
Osteoporotic Fractures - drug therapy
Osteoporotic Fractures - prevention & control
Pharmacology
Post-menopause
Risk assessment
Teriparatide - pharmacology
Teriparatide - therapeutic use
Womens health
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Summary:Osteoporosis is a systemic skeletal disease that is a cause of morbidity and mortality. It can affect all ages but most frequently postmenopausal women. It is a silent condition, however, osteoporotic fractures can lead to significant pain and disability. In this review article, we aim to review the clinical approach to the management of postmenopausal osteoporosis. We include risk assessment, investigations, and the various pharmacological and non-pharmacological options used in the treatment of osteoporosis. We have discussed the pharmacological options individually including their mechanism of action, safety profile, effects on bone mineral density and fracture risks, and duration of use. Potential new treatments are also discussed. The importance of sequence in the use of osteoporotic medicine is also highlighted in the article. An understanding of the different treatment options will hopefully help in the management of this very common and debilitating condition.
ISSN:1745-5057
1745-5065
DOI:10.1177/17455057231176655