Case Report: A Virilizing Adrenal Oncocytoma

A 64-year-old female was admitted to our clinic with a 9-cm-sized adrenal mass. The patient's main symptom was hirsutism, which included thinning scalp hair and excessive hair growth over her torso and arms. Upon investigation, elevated values of testosterone, androsterone D4, and DHEA-S were f...

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Bibliographic Details
Published in:Frontiers in surgery 2021-03, Vol.8, p.646459
Main Authors: Kotidis, Efstathios, Bitsianis, Stefanos, Galanos-Demiris, Konstantinos, Christidis, Panagiotis, Mantzoros, Ioannis, Ioannidis, Orestis, Foutsitzis, Vasilis, Pramateftakis, Manousos George, Aggelopoulos, Stamatios
Format: Article
Language:English
Subjects:
adrenal mass
borderline
masculinization
oncocytoma
Surgery
testosterone
virilization
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Summary:A 64-year-old female was admitted to our clinic with a 9-cm-sized adrenal mass. The patient's main symptom was hirsutism, which included thinning scalp hair and excessive hair growth over her torso and arms. Upon investigation, elevated values of testosterone, androsterone D4, and DHEA-S were found. Contrast-enhanced abdominal CT and MRI scans revealed a heterogenous large mass (diameter 9 × 8.5 cm) with focal calcifications, necrotic areas, and a clear distinction from the adjacent structures. The patient underwent a right adrenalectomy. The histological examination of the tumor revealed a borderline adrenocortical oncocytoma. The patient had an uncomplicated postoperative course and was discharged on postoperative day 8. Similar cases reported in the literature are also being reviewed in this case report.
ISSN:2296-875X
2296-875X
DOI:10.3389/fsurg.2021.646459