Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal...

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Bibliographic Details
Published in:Frontiers in microbiology 2020-09, Vol.11, p.573430-573430
Main Authors: Shen, Lishuang, Dien Bard, Jennifer, Biegel, Jaclyn A, Judkins, Alexander R, Gai, Xiaowu
Format: Article
Language:English
Subjects:
COVID-19
haplotype
localized outbreak
Microbiology
SARS-CoV-2
temporal transmission
variant
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Summary:Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness of existing travel restriction policies and public health measures in reducing the transmission of SARS-CoV-2.
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2020.573430