ROLE OF ORAL ONDANSETRON AS AN ADJUCNT TO ORAL REHYDRATION THERAPY IN ACUTE GASTROENTERITIS

Objective: To evaluate the role of oral ondansetron as an effective measure to facilitate oral rehydration in acute gastroenteritis.Study Design: Randomized controlled trail.Place and Duration of Study: Army medical college, Military hospital Rawalpindi, from Mar 2017 to Sep 2017.Material and Method...

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Bibliographic Details
Published in:Pakistan Armed Forces medical journal 2018-08, Vol.68 (4), p.1003-1006
Main Authors: Amin, Mehwish, Khan, Muhammad Waqar Aslam
Format: Article
Language:English
Subjects:
acute gastroenteritis
Children & youth
Clinical trials
dehydration
Dehydration (Physiology)
Diarrhea
Gastroenteritis
Gastrointestinal diseases
Hospitals
Hydration
Hyperglycemia
Malnutrition
Medical schools
Mortality
Pediatrics
Systematic review
Vomiting
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Summary:Objective: To evaluate the role of oral ondansetron as an effective measure to facilitate oral rehydration in acute gastroenteritis.Study Design: Randomized controlled trail.Place and Duration of Study: Army medical college, Military hospital Rawalpindi, from Mar 2017 to Sep 2017.Material and Methods: One hundred and forty children with clinical diagnosis of acute gastroenteritis with mild to moderate dehydration were randomized into two equal groups. Group 1 was treated according to the WHO criteria with only ORS in a dose of 75ml/kg body weight. Group 2 received ondansetron before ORS as a single oral dose of 0.2mg/kg body weight.Results: The difference between improvement in drinking abihty and hydration status between the two groups was highly significant (p
ISSN:0030-9648
2411-8842