Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) in infants (

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Bibliographic Details
Published in:Biomedicines 2021-06, Vol.9 (7), p.711
Main Authors: Kerstjens, Mark, Garrido Castro, Patricia, Pinhanços, Sandra S., Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.
Format: Article
Language:English
Subjects:
Acute lymphoblastic leukemia
Animal models
Apoptosis
Camptothecin
Cell culture
Children
Chromosome translocations
DNA methylation
Drug screening
Drugs
Epigenetics
Flow cytometry
Gene expression
Infants
Irinotecan
Leukemia
Lymphatic leukemia
Malignancy
Medical prognosis
MLL translocation
pediatric acute leukemia
Pediatrics
Remission
Remission (Medicine)
Software
Solid tumors
xenograft mouse models
Xenografts
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Description
Summary:Acute lymphoblastic leukemia (ALL) in infants (
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines9070711