The efficacy of midline catheters—a prospective, randomized, active-controlled study

•Midline catheters can be inserted with ultrasound guidance at the bedside.•A midline catheter-based strategy reduced the need for central venous catheters.•The complication-free catheter survival time was 15 days in the midline group.•A midline catheter-based strategy reduced personnel time expendi...

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Bibliographic Details
Published in:International journal of infectious diseases 2021-01, Vol.102, p.220-225
Main Authors: Nielsen, Emma Bundgaard, Antonsen, Louise, Mensel, Camilla, Milandt, Nikolaj, Dalgaard, Lars Skov, Illum, Britta Skov, Arildsen, Hanne, Juhl-Olsen, Peter
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Catheterization, Central Venous - adverse effects
Catheterization, Peripheral - adverse effects
Central Venous Catheters
Female
Humans
Intravenous catheter
Intravenous therapy
Male
Middle Aged
Midline catheter
PICC
Prospective Studies
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Summary:•Midline catheters can be inserted with ultrasound guidance at the bedside.•A midline catheter-based strategy reduced the need for central venous catheters.•The complication-free catheter survival time was 15 days in the midline group.•A midline catheter-based strategy reduced personnel time expenditure. This study was performed to investigate whether an intravenous (IV) strategy based on new-generation midline catheters is an efficacious alternative to a conventional IV strategy consisting of peripheral venous catheters and central venous catheters, for patients needing IV therapy exceeding 5 days. This was a prospective, randomized, controlled study. Patients requiring more than 5 days of IV treatment were randomized to either a midline catheter-based IV strategy or a conventional strategy. The primary endpoint was the composite of the insertion of a central venous catheter (CVC) or the need for four or more peripheral venous catheter (PVC) insertions. The secondary outcomes included catheter dwell times and reasons for premature removal. One hundred and twenty patients were included. The fraction of patients receiving four or more PVCs or having a CVC inserted was 12/58 (21%) in the midline group versus 38/58 (66%) in the conventional group (p 
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2020.10.053