Genomic signatures associated with maintenance of genome stability and venom turnover in two parasitoid wasps

• Published in: Nature communications 2022-10, Vol.13 (1), p.6417-17, Article 6417
• Main Authors: Ye, Xinhai, Yang, Yi, Zhao, Can, Xiao, Shan, Sun, Yu H., He, Chun, Xiong, Shijiao, Zhao, Xianxin, Zhang, Bo, Lin, Haiwei, Shi, Jiamin, Mei, Yang, Xu, Hongxing, Fang, Qi, Wu, Fei, Li, Dunsong, Ye, Gongyin
• Format: Article
• Language: English
• Subjects: 45; 45/23; 45/91; 631/181/2474; 631/181/735; 631/208/212/2304; Anastatus; Animals; Biology; Coevolution; Developmental biology; DNA Transposable Elements - genetics; Evolution; Evolutionary biology; Evolutionary genetics; Genes; Genomes; Genomic Instability - genetics; Genomics; Humanities and Social Sciences; Innovations; Insects; Maintenance; multidisciplinary; Parasitoids; Piwi gene; Science; Science (multidisciplinary); Stability; Transposons; Venom gland; Venoms; Wasps - genetics
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/s41467-022-34202-y

Parasitoid wasps are rapidly developing as a model for evolutionary biology. Here we present chromosomal genomes of two Anastatus wasps, A. japonicus and A. fulloi , and leverage these genomes to study two fundamental questions—genome size evolution and venom evolution. Anastatus shows a much larger genome than is known among other wasps, with unexpectedly recent bursts of LTR retrotransposons. Importantly, several genomic innovations, including Piwi gene family expansion, ubiquitous Piwi expression profiles, as well as transposable element-piRNA coevolution, have likely emerged for transposable element silencing to maintain genomic stability. Additionally, we show that the co-option evolution arose by expression shifts in the venom gland plays a dominant role in venom turnover. We also highlight the potential importance of non-venom genes that are coexpressed with venom genes during venom evolution. Our findings greatly advance the current understanding of genome size evolution and venom evolution, and these genomic resources will facilitate comparative genomics studies of insects in the future. Parasitoid wasps are rapidly developing as a model for evolutionary biology. Here, the authors analyze the genomes of two Anastatus wasps, revealing genomic innovations related to maintenance of genomic stability, and rapid turnover of venom genes.