Characteristics and outcomes of severe COVID-19 in hospitalized patients with cardiovascular diseases in the Amazonian region of Brazil: a retrospective cohort

• Published in: Scientific reports 2022-11, Vol.12 (1), p.18472-18472, Article 18472
• Main Authors: Sardinha, Daniele Melo, de Sá, Carmem Aliandra Freire, Rodrigues, Yan Corrêa, dos Santos Freitas, Joyce, Brodeur, Ketan, do Socorro Pompeu de Loiola, Rosane, Lima, Karla Valéria Batista, de Paula Souza e Guimarães, Ricardo José, Lima, Luana Nepomuceno Gondim Costa
• Format: Article
• Language: English
• Subjects: 692/1807; 692/4019; 692/499; 692/699/1785; Age; Age groups; Brazil - epidemiology; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cardiovascular Diseases - therapy; Coronaviruses; Cough; Cough - complications; COVID-19; COVID-19 - epidemiology; COVID-19 - therapy; Diabetes mellitus; Dyspnea; Dyspnea - complications; Humanities and Social Sciences; Humans; Infectious diseases; Kidney diseases; Mechanical ventilation; Middle Aged; Morbidity; multidisciplinary; Patients; Respiration; Retrospective Studies; Science; Science (multidisciplinary); Survival
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-23365-9

The northern region of Brazil is already vulnerable to other infectious diseases and it was no different in COVID-19. However, cardiovascular diseases still lead the causes of death. Thus, the objective of this study is to identify the clinical predictors and outcome of severe COVID-19 in hospitalized patients with and without CVD in this region of the Amazon. A retrospective cohort, referring to the notifications from January 1 to December 31, 2020, including cases confirmed by molecular testing. The study consisted of 9223 confirmed cases for COVID-19. Of these, 6011 (65.17%) did not have cardiovascular disease and 3212 (34.83%) had some cardiovascular disease. The significance of deaths was in the age group of