Anemia among Chinese patients with chronic kidney disease and its association with quality of life - results from the Chinese cohort study of chronic kidney disease (C-STRIDE)

Anemia is one of the common complications in patients with chronic kidney disease (CKD). However, there is no systematic investigation on the prevalence of anemia in CKD patients and its relationship with the quality of life in China. The data for this study comes from baseline data from the Chinese...

Full description

Saved in:
Bibliographic Details
Published in:BMC nephrology 2021-02, Vol.22 (1), p.64-64, Article 64
Main Authors: Shen, Yan, Wang, Jinwei, Yuan, Jing, Yang, Li, Yu, Fangfang, Wang, Xiaolei, Zhao, Ming-Hui, Zhang, Luxia, Zha, Yan
Format: Article
Language:English
Subjects:
Age
Anemia
Blood pressure
C-STRIDE
Chinese patients
Chronic kidney disease
Chronic kidney failure
Cohort analysis
Complications and side effects
Creatinine
Diabetes
Education
Epidermal growth factor receptors
Generalized linear models
Health aspects
Hemoglobin
Hypertension
Iron
Kidney diseases
Nephrology
Quality of life
Quality of life - results
Risk factors
Surveys
Variables
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Anemia is one of the common complications in patients with chronic kidney disease (CKD). However, there is no systematic investigation on the prevalence of anemia in CKD patients and its relationship with the quality of life in China. The data for this study comes from baseline data from the Chinese Chronic Kidney Disease Cohort Study (C-STRIDE), which recruited predialysis CKD patients in China. The kidney disease quality of life summary (KDQOL-TM) was used to assess health-related quality of life (HRQoL). Use linear regression model to estimate the relationship between hemoglobin level and quality of life. A total of 2921 patients were included in this study. The adjusted prevalence of hemoglobin (Hb) less than 100 g/L was 10.3% (95% confidence interval [CI]: 9.9,11.4%), and showed an increased trend through reduced eGFR levels from 4.0% (95%CI:2.3,5.9%) in the 45-60 ml/min/1.73m group to 23.4% (95%CI:20.5,26.2%) in the 15-29 ml/min/1.73m group. The prevalence of anti-anemia treatment was 34.0% (95%CI: 28.7,39.3%) and it is shown by reducing eGFR levels from 15.8% (95%CI:0,36.7%) in the 45-60 ml/min/1.73m group to 38.2% (95%CI: 30.7,45.2%) in the 15-29 ml/min/1.73m group. All five dimensions of the KDQOL scores in patients with CKD decreased as hemoglobin declined. After multivariable adjustments,the degrees of decrease became somewhat blunted. For example, compared with hemoglobin of ≥130 g/L, regression coefficients in the hemoglobin of
ISSN:1471-2369
1471-2369
DOI:10.1186/s12882-021-02247-8