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Neat synthesis and antioxidant activity of α-aminophosphonates

A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde and diethyl phosphite catalyzed by Amberlyst-15 has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions using microw...

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Bibliographic Details
Published in:Arabian journal of chemistry 2014-11, Vol.7 (5), p.833-838
Main Authors: Subba Reddy, Guna, Uma Maheswara Rao, Kunda, Syama Sundar, Chereddy, Sudha, Sarva Santhi, Haritha, Buchammagari, Swapna, Sirasanagandla, Suresh Reddy, Cirandur
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Language:English
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Summary:A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde and diethyl phosphite catalyzed by Amberlyst-15 has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions using microwave irradiation. The major advantages of the present method are inexpensive, ecofriendly and reusable catalyst and also studied their antioxidant activity of synthesized compounds.
ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2013.01.004