Palliative endoscopic retrograde biliary drainage for malignant biliary obstruction in Korea: A nationwide assessment

• Published in: Saudi journal of gastroenterology 2021-05, Vol.27 (3), p.173-177
• Main Authors: Jang, Dong, Kim, Jungmee, Yoon, Seung, Yoon, Won, Kim, Jung-Wook, Lee, Tae, Jang, Jae-Young, Paik, Chang, Lee, Jun
• Format: Article
• Language: English
• Subjects: Aged; biliary tract neoplasms; Cancer; Cholangiocarcinoma; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis - epidemiology; Cholestasis - etiology; Cholestasis - surgery; Drainage; endoscopic retrograde cholangiopancreatography; Endoscopy; Humans; korea; Male; Management buyouts; Middle Aged; obstructive jaundice; Oncology, Experimental; Original; Pancreatic cancer; pancreatic neoplasms; Pancreatic Neoplasms - complications; Pancreatic Neoplasms - epidemiology; Republic of Korea - epidemiology; Retrospective Studies; Stents; Treatment Outcome
• ISSN: 1319-3767; 1998-4049
• DOI: 10.4103/sjg.sjg_589_20

Background: Malignant biliary obstruction (MBO) is usually caused by biliary tract cancer or pancreatic cancer. This study was performed to summarize the current situation regarding palliative endoscopic retrograde biliary drainage (ERBD) for MBO in Korea and to determine its clinical significance by analyzing representative nationwide data. Methods: Patients that underwent palliative ERBD for MBO between 2012 and 2015 were identified using the Health Insurance Review and Assessment database, which covers the entire Korean population. We assessed clinical characteristics and complications and compared the clinical impacts of initial metal and plastic stenting in these patients. Results: A total of 9,728 subjects (mean age, 65 ± 11.4 years; male, 61.4%) were identified and analyzed. The most common diagnosis was malignant neoplasm of liver and intrahepatic bile ducts (32.1%) and this was followed by extrahepatic or Ampulla of Vater cancer and pancreatic cancer. Initial plastic stent(s) placement was performed in 52.9% of the study subjects, and metal stent(s) placement was performed in 23.3%. The number of sessions of endoscopic retrograde cholangiopancreatography (ERCP) or percutaneous transhepatic biliary drainage (PTBD) was significantly higher in patients that underwent initial plastic stenting than in patients that underwent metal stenting (2.2 ± 1.7 vs 1.8 ± 1.4, P < 0.0001), but rates of post-ERCP pancreatitis, hospital days, and time to second ERCP or PTBD were not significantly different. Conclusion: This nationwide assessment study suggests that initial metal stenting is associated with fewer sessions of total ERCP or PTBD following the initial procedure, despite the preference for initial plastic stenting in Korea.