Direct and indirect costs of cluster headache: a prospective analysis in a tertiary level headache centre

Background Cluster headache (CH) is the most frequent trigemino-autonomic cephalgia. CH can manifest as episodic (ECH) or chronic cluster headache (CCH) causing significant burden of disease and requiring attack therapy and prophylactic treatment. The few data available on the economic burden of CH...

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Bibliographic Details
Published in:Journal of headache and pain 2020-05, Vol.21 (1), p.44-44, Article 44
Main Authors: Negro, Andrea, Sciattella, Paolo, Spuntarelli, Valerio, Martelletti, Paolo, Mennini, Francesco Saverio
Format: Article
Language:English
Subjects:
Burden of disease
Chronic cluster headache
Cluster headache
Cost of illness
Costs
Episodic cluster headache
Headache
Headaches
Internal Medicine
Medicine
Medicine & Public Health
Neurology
Pain management
Pain Medicine
Patients
Population studies
Research Article
Resource utilization
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Summary:Background Cluster headache (CH) is the most frequent trigemino-autonomic cephalgia. CH can manifest as episodic (ECH) or chronic cluster headache (CCH) causing significant burden of disease and requiring attack therapy and prophylactic treatment. The few data available on the economic burden of CH come from retrospective studies based on questionnaires, population surveys and medical insurance claims database. Although all these studies showed an important economic burden, they provided different estimates depending on variability of CH awareness and management, healthcare systems, available therapies and use of treatments according to different guidelines. Methods This prospective study aimed to quantify the total direct and indirect cost of ECH and CCH over a cluster period, both for the patient and for the National Health System (NHS), using data from subjects who consecutively attended an Italian tertiary headache centre between January 1, 2018 and December 31, 2018. Results A total 108 patients (89 ECH, 19 CCH) were included. Mean attack frequency was 2.3 ± 1.4 per day. Mean total cost of a CH bout was €4398 per patient and total cost of CCH was 5.4 times higher than ECH (€13,350 vs. €2487, p  
ISSN:1129-2369
1129-2377
DOI:10.1186/s10194-020-01115-4