Antibacterial Effects of Silver Diamine Fluoride with and without Potassium Iodide against Streptococcus mutans

• Published in: Contemporary clinical dentistry 2024-01, Vol.15 (1), p.22-26
• Main Authors: Alvarez-Marín, Carlos Alonso, Robles-Bermeo, Norma Leticia, Hassan Moustafa, Wael Hegazy, Medina-Solís, Carlo Eduardo
• Format: Article
• Language: English
• Subjects: Antibacterial activity; Antibacterial agents; antibacterial effect; Care and treatment; Complications and side effects; dental biofilm; Dental caries; Dental roots; Diagnosis; Dosage and administration; Fluoride treatments; Fluorides; Health aspects; Medicine, Preventive; Methods; Molars; Potassium; Potassium iodide; Preventive health services; Properties; Risk factors; silver diamine fluoride; Statistical analysis; Statistics; Streptococcal infections; Streptococcus mutans
• ISSN: 0976-237X; 0976-2361
• DOI: 10.4103/ccd.ccd_393_23

Silver diamine fluoride (SDF) is a topical treatment for carious lesions and a primary preventative for newly exposed high-risk surfaces such as fissures and roots in the first molars. Using potassium iodide (KI) after applying SDF has been recommended as a way of reducing the severity of black staining, as well as preserving its antibacterial effect useful in deep caries. The objective of this research was to compare the antibacterial effect of SDF, with and without KI, on ( . ) and dental biofilm. The antibacterial effects of SDF, KI, and the combination of both were measured using three different techniques (inhibition halo, minimum inhibitory effect [MIE], and colony-forming unit [CFU], testing). The results were then subjected to statistical analysis. Analyzed by means of the Kruskal-Wallis statistical test, the inhibition halos yielded a value of = 0.3309. Using the MIE test, only the SDF treatment produced an antibacterial effect, at 10%, compared to the KI group, with = 0.001. Finally, the CFU test revealed a total absence of colonies for all three reagents. All three substances analyzed achieved total inhibition of . . SDF is effective even in its minimal commercial concentration. Its antibacterial capacity decreases with the addition of KI. The three substances analyzed at their maximum concentrations exhibited an antibacterial effect against . , resulting in total inhibition.