Familial incidence of mammary gland tumours in the Djungarian hamster (Phodopus sungaros): a case report

Tumours of the mammary gland were diagnosed in one female Djungarian hamster (Phodopus sungaros) and in two of her daughters from two litters. Altogether, five tumours were diagnosed. Three of them were adenocarcinomas, one was adenoma with disseminated foci of adenocarcinoma and one was diagnosed a...

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Bibliographic Details
Published in:Veterinární medicína 2013-08, Vol.58 (8), p.442-448
Main Authors: Jelinek, F., Felsberg, J., Mestan, M.
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adenoma
atypical fibrosarcoma
clinic
Deoxyribonucleic acid
DNA
Fibrosarcoma
hamsters
Mammary gland
Mammary glands
molecular biology
neoplasias
Paraffin
Paraffins
pathology
Phodopus
Tumors
Viruses
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Summary:Tumours of the mammary gland were diagnosed in one female Djungarian hamster (Phodopus sungaros) and in two of her daughters from two litters. Altogether, five tumours were diagnosed. Three of them were adenocarcinomas, one was adenoma with disseminated foci of adenocarcinoma and one was diagnosed as an atypical fibrosarcoma derived from cutaneous ganglion cell-like cells. This was a recurrent tumour in the proximity of the previously extirpated adenocarcinoma. Using specific PCR primers for conserved regions of the mouse mammary tumour virus (MMTV) no endogenous provirus DNA could be detected in DNA samples isolated from formalin-fixed paraffin embedded tissue sections.
ISSN:0375-8427
1805-9392
DOI:10.17221/6985-VETMED