Association between the triglyceride–glucose index and severity of coronary artery disease

Background The triglyceride–glucose (TyG) index, which is a reliable surrogate marker of insulin resistance (IR), has been associated with cardiovascular diseases. However, evidence of the impact of the TyG index on the severity of coronary artery disease (CAD) is limited. This study investigated th...

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Bibliographic Details
Published in:Cardiovascular diabetology 2022-09, Vol.21 (1), p.1-168, Article 168
Main Authors: Wang, Xiang, Xu, Wei, Song, Qirui, Zhao, Zinan, Meng, Xuyang, Xia, Chenxi, Xie, Yibo, Yang, Chenguang, Jin, Pengfei, Wang, Fang
Format: Article
Language:English
Subjects:
Age
Antihypertensives
Body mass index
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Coronary artery
Coronary artery disease
Coronary vessels
Creatinine
Diabetes
Diabetes mellitus
Drug use
Fasting
Glomerular filtration rate
Glucose
Heart diseases
High density lipoprotein
Hospitals
Hypertension
Insulin
Insulin resistance
Kidney diseases
Laboratories
Metabolism
Plasma
Regression analysis
Risk factors
Sociodemographics
Statistical analysis
Triglyceride–glucose index
Variables
Vein & artery diseases
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Summary:Background The triglyceride–glucose (TyG) index, which is a reliable surrogate marker of insulin resistance (IR), has been associated with cardiovascular diseases. However, evidence of the impact of the TyG index on the severity of coronary artery disease (CAD) is limited. This study investigated the relationship between the TyG index and CAD severity of individuals with different glucose metabolic statuses. Methods This study enrolled 2792 participants with CAD in China between January 1, 2018 and December 31, 2021. All participants were divided into groups according to the tertiles of the TyG index as follows: T1 group, TyG index 
ISSN:1475-2840
1475-2840
DOI:10.1186/s12933-022-01606-5