Lipofibroadenoma with B1 thymoma: A case report of a rare thymic tumor

Hematological parameters revealed hemoglobin – 12.7 g%, packed cell volume – 38.9%, total white blood cell count – 12,900/mm3, and platelet count – 2.9 lakhs/mm3. Magnetic resonance imaging revealed a well-marginated lesion measuring 54 mm × 24 mm × 65 mm separated from the mediastinal vessels with...

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Bibliographic Details
Published in:Indian journal of pathology & microbiology 2018-10, Vol.61 (4), p.630-632
Main Authors: Hui, Monalisa, Paul, Tara, Uppin, Shantveer, Jyothi, Nirmala
Format: Article
Language:English
Subjects:
Adipose tissue
Adult
Antigens, CD20 - analysis
Blood vessels
Breast
Calcification
Case reports
CD20 antigen
CD3 antigen
CD3 Complex - analysis
Cell size
Computed tomography
Corpuscles
Cysts
Cytokeratin
DNA nucleotidylexotransferase
Dyspnea
Fetal Proteins - analysis
Fibroadenoma
Fibroadenoma - diagnosis
Fibroadenoma - pathology
Fibroadenoma - surgery
Hematology
Hemoglobin
Humans
Immunohistochemistry
Leukocytes
Lymphoid cells
Magnetic resonance imaging
Male
Morphology
Neoplasia
Positron emission
Positron emission tomography
Stroma
T-Box Domain Proteins - analysis
Thymectomy
Thymoma
Thymoma - diagnosis
Thymoma - pathology
Thymoma - surgery
Thymus
Thymus Gland - cytology
Thymus Gland - pathology
Thymus Gland - surgery
Thymus Neoplasms - diagnosis
Thymus Neoplasms - pathology
Thymus Neoplasms - surgery
Tumors
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Summary:Hematological parameters revealed hemoglobin – 12.7 g%, packed cell volume – 38.9%, total white blood cell count – 12,900/mm3, and platelet count – 2.9 lakhs/mm3. Magnetic resonance imaging revealed a well-marginated lesion measuring 54 mm × 24 mm × 65 mm separated from the mediastinal vessels with preserved fat planes, suggestive of benign thymic neoplasm [Figure 1]b. Positron emission tomography CT scan showed an anterior mediastinal mass with no fluorodeoxyglucose uptake, suggestive of pericardial cyst/thymoma. The morphology resembled fibroadenoma of the breast [Figure 1]c and [Figure 1]d. Lobules of adipose tissue, calcification, and lymphoid cells with Hassall's corpuscles were entrapped in the stroma [Figure 1]e. The adjacent areas showed type B1 thymoma [Figure 1]f, [Figure 1]g, [Figure 1]h. Immunohistochemistry was done with cytokeratin (CK) 19, CD3, CD20, and Tdt.
ISSN:0377-4929
0974-5130
DOI:10.4103/IJPM.IJPM_443_17