Advances in the Treatment of Pediatric Brain Tumors

Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clini...

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Bibliographic Details
Published in:Children (Basel) 2022-12, Vol.10 (1), p.62
Main Authors: Kulubya, Edwin S, Kercher, Matthew J, Phillips, H Westley, Antony, Reuben, Edwards, Michael S B
Format: Article
Language:English
Subjects:
Accuracy
Biopsy
Brain cancer
Brain research
brain tumors
Chemotherapy
Endoscopy
ependymoma
Gene expression
Glioma
Headaches
Hydrocephalus
Immunotherapy
Intracranial pressure
Kinases
Magnetic resonance imaging
Medical prognosis
medulloblastoma
Metabolism
Mutation
Nervous system
Oncology
Patients
Pediatrics
Radiation
Review
Surgery
Surveillance
Tumors
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Summary:Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
ISSN:2227-9067
2227-9067
DOI:10.3390/children10010062