Exploration and machine learning model development for T2 NSCLC with bronchus infiltration and obstructive pneumonia/atelectasis

In the 8th edition of the American Joint Committee on Cancer (AJCC) staging system for Non-Small Cell Lung Cancer (NSCLC), tumors exhibiting main bronchial infiltration (MBI) near the carina and those presenting with complete lung obstructive pneumonia/atelectasis (P/ATL) have been reclassified from...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2024-02, Vol.14 (1), p.4793-4793, Article 4793
Main Authors: Jin, Xuanhong, Pan, Yang, Zhai, Chongya, shen, Hangchen, You, Liangkun, Pan, Hongming
Format: Article
Language:English
Subjects:
631/67/1612
631/67/70
Adjuvant therapy
Atelectasis
Bronchus
Epidemiology
Humanities and Social Sciences
Induction therapy
Infiltration
Lung cancer
Lymph nodes
Medical prognosis
Metastases
multidisciplinary
Non-small cell lung carcinoma
Patients
Pneumonia
Prognosis
Science
Science (multidisciplinary)
Small cell lung carcinoma
Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the 8th edition of the American Joint Committee on Cancer (AJCC) staging system for Non-Small Cell Lung Cancer (NSCLC), tumors exhibiting main bronchial infiltration (MBI) near the carina and those presenting with complete lung obstructive pneumonia/atelectasis (P/ATL) have been reclassified from T3 to T2. Our investigation into the Surveillance, Epidemiology, and End Results (SEER) database, spanning from 2007 to 2015 and adjusted via Propensity Score Matching (PSM) for additional variables, disclosed a notably inferior overall survival (OS) for patients afflicted with these conditions. Specifically, individuals with P/ATL experienced a median OS of 12 months compared to 15 months (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-55507-6