Anatomical factors influencing temporomandibular joint clicking in young adults: temporomandibular joint structure disorder or lateral pterygoid muscle dysfunction?

• Published in: Frontiers in bioengineering and biotechnology 2024-05, Vol.12, p.1337267-1337267
• Main Authors: Luo, Dan, Yang, Hua, Yuan, Mujie, Wang, Dashan, Qiu, Cheng, Zhou, Ruizhi, Gao, Yudong, Xu, Ruijie, Yang, Jianjun, Xu, Zexian
• Format: Article
• Language: English
• Subjects: Bioengineering and Biotechnology; joint structure; lateral pterygoid muscle; masticatory muscle function; temporomandibular joint clicking; texture analysis
• ISSN: 2296-4185; 2296-4185
• DOI: 10.3389/fbioe.2024.1337267

This study aimed to investigate the selected anatomical factors that can potentially influence temporomandibular joint (TMJ) clicking in young adults by assessing TMJ structures and lateral pterygoid muscle (LPM) function using magnetic resonance imaging (MRI). The patients were divided into four groups: the healthy control group; the clicking on mouth opening group; the clicking on mouth closing group; and the clicking on mouth opening and closing group. Additionally, we used clinical palpation to evaluate the masticatory muscles' functional state and employed MRI using the OCOR-T1WI-FSE-CLOSED, OSAG-PDW-FSE-CLOSED, and OSAG-PDW-FSE-OPEN sequences to analyze the texture of the lateral pterygoid muscle (LPM). The proportion of any articular disc or condylar morphology class did not differ significantly between the TMJ clicking and HC groups. The articular disc position did not differ significantly between the TMJ clicking and HC groups. In the TMJ clicking group, the presence of masticatory muscle dysfunction differed significantly between the clicking and non-clicking sides. Moreover, the LPM accounted for the highest proportion among masticatory muscles with tenderness in all TMJ clicking subgroups (77.78%-100%). Therefore, in the TMJ clicking group, the LPM texture was less defined, more uniform in gray scale, and more similar to local texture ( < 0.0001). The occurrence of TMJ clicking in young adults is unrelated to the TMJ structure but related to the function of masticatory muscles, particularly the LPM.