Oxidative Stress in Multiple Sclerosis Disease (Review Article)

Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, in which the myelin sheaths got injured. The prevalence of MS is on grow, as well as, it affects the young ages. Females are most common to have MS compared to males. Oxidative stress is the situation of im...

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Published in:Diyala Journal of Medicine 2021-12, Vol.21 (2), p.33-40
Main Authors: Mohammed Kadhim, Sura, Mohsin Abbood, Sura, Mohammed Taay, Yasser, Taha Mohammed, Mustafa
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Language:English
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Oxidative stress, ROS, multiple sclerosis, antioxidants
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Mohsin Abbood, Sura
Mohammed Taay, Yasser
Taha Mohammed, Mustafa
description Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, in which the myelin sheaths got injured. The prevalence of MS is on grow, as well as, it affects the young ages. Females are most common to have MS compared to males. Oxidative stress is the situation of imbalance between oxidants (free radicals and reactive oxygen species (ROS)) and antioxidants in a living system, in which either the oxidants are elevated or antioxidants are reduced, or sometimes both. ROS and oxidative stress have been implicated in the progression of many degenerative diseases, which is important in cracking the unrevealed mysteries of MS. In this review article, some of the proposed mechanisms that link oxidative stress with MS disease would be described. Keywords: Oxidative stress, ROS, multiple sclerosis, antioxidants
doi_str_mv 10.26505/DJM.21026040523
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subjects Oxidative stress, ROS, multiple sclerosis, antioxidants
title Oxidative Stress in Multiple Sclerosis Disease (Review Article)
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