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Mexican Plants Involved in Glucose Homeostasis and Body Weight Control: Systematic Review

Obesity is defined as abnormal or excessive fat accumulation, provoking many different diseases, such as obesity and type 2 diabetes. Type 2 diabetes is a chronic-degenerative disease characterized by increased blood glucose levels. Obesity and type 2 diabetes are currently considered public health...

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Published in:Nutrients 2023-04, Vol.15 (9), p.2070
Main Authors: Torres-Vanda, Montserrat, Gutiérrez-Aguilar, Ruth
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description Obesity is defined as abnormal or excessive fat accumulation, provoking many different diseases, such as obesity and type 2 diabetes. Type 2 diabetes is a chronic-degenerative disease characterized by increased blood glucose levels. Obesity and type 2 diabetes are currently considered public health problems, and their prevalence has increased over the last few years. Because of the high cost involved in the treatment of both diseases, different alternatives have been sought. However, the general population uses medicinal plants, in the form of tea or infusions, to treat different diseases. Therefore, traditional medicine using medicinal plants has been investigated as a possible treatment for type 2 diabetes and body weight control. The purpose of this review is to find medicinal plants used in Mexico that could exert their beneficial effect by regulating insulin secretion and body weight control. For the development of this review, Mexican plants used in traditional medicine to treat type 2 diabetes and body weight control were searched in PubMed, Google Scholar, and Scopus. The inclusion criteria include plants that presented a significant reduction in blood glucose levels and/or an increase in insulin secretion. We found 306 Mexican plants with hypoglycemic effects. However, plants that did not show evidence of an increase in insulin secretion were eliminated. Finally, only five plants were included in this review: L. ( ), ( ), L. ( ), Mill. ( ) ( ), including 39 articles in total. Here, we summarized the plant extracts (aqueous and organic) that have previously been reported to present hypoglycemic effects, body weight control, increased secretion and sensitivity of insulin, improvement of pancreatic β cells, and glucose tolerance. Additionally, these effects may be due to different bioactive compounds present in the plants' extracts. Both in vivo and in vitro studies are required to understand the mechanism of action of these plant extracts regarding insulin secretion to be used as a possible treatment for type 2 diabetes and body weight control in the future.
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ispartof Nutrients, 2023-04, Vol.15 (9), p.2070
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subjects Beta cells
Bioactive compounds
Biological products
Blood
Blood Glucose
Blood sugar
Body Weight
body weight control
Coriandrum
Cucurbita
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - drug therapy
Diseases
Glucose
glucose homeostasis
Glucose tolerance
Health problems
Health services
Herbal medicine
Homeostasis
Humans
Hypoglycemic Agents
In vivo methods and tests
Insulin
Insulin secretion
Medicinal plants
Medicine
Medicine, Botanic
Medicine, Herbal
Metabolism
Mexico
Obesity
Obesity - drug therapy
Overweight
Plant extracts
Public health
Review
Reviews
Secretion
Seeds
Systematic review
Type 2 diabetes
Weight control
title Mexican Plants Involved in Glucose Homeostasis and Body Weight Control: Systematic Review
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