Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort

Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-term exposure to particulate matter with a diameter 

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Bibliographic Details
Published in:Environmental health 2017-06, Vol.16 (1), p.52-52, Article 52
Main Authors: Winckelmans, Ellen, Vrijens, Karen, Tsamou, Maria, Janssen, Bram G, Saenen, Nelly D, Roels, Harry A, Kleinjans, Jos, Lefebvre, Wouter, Vanpoucke, Charlotte, de Kok, Theo M, Nawrot, Tim S
Format: Article
Language:English
Subjects:
Adolescent
Adult
Air Pollutants - analysis
Air Pollutants - toxicity
Air pollution
Airborne particulates
Alcohol
Ambient air pollution
Belgium
Birth weight
Cancer
Childbirth & labor
Cohort Studies
Cord blood
Damage
Deoxyribonucleic acid
DNA
DNA damage
DNA microarrays
Education
Environmental health
Ethnicity
Exposure
Female
Fetal
Fetal Blood - chemistry
Fetuses
Gene expression
Gene set enrichment analysis
Genomes
Girls
Grandparents
Health aspects
Health problems
Health risk assessment
Humans
Immune response
Immune system
Infant, Newborn
Infants (Newborn)
Interpolation
Kinases
Male
Maternal Exposure
Microarray analysis
Mitochondria
Mothers
Neurodevelopment
Outdoor air quality
Parent educational background
Particulate matter
Particulate Matter - analysis
Particulate Matter - toxicity
Pregnancy
RhoA protein
Rope
Sex
Sex Factors
Signatures
Synaptic transmission
Transcriptome - drug effects
Young Adult
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Description
Summary:Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-term exposure to particulate matter with a diameter 
ISSN:1476-069X
1476-069X
DOI:10.1186/s12940-017-0264-y