A Model for the Gene Regulatory Network Along the Arabidopsis Fruit Medio-Lateral Axis: Rewiring the Pod Shatter Process

Different convergent evolutionary strategies adopted by angiosperm fruits lead to diverse functional seed dispersal units. Dry dehiscent fruits are a common type of fruit, characterized by their lack of fleshy pericarp and the release of seeds at maturity through openings (dehiscence zones, DZs) in...

Full description

Saved in:
Bibliographic Details
Published in:Plants (Basel) 2024-10, Vol.13 (20), p.2927
Main Authors: Moya-Cuevas, José, Ortiz-Gutiérrez, Elizabeth, López-Sánchez, Patricio, Simón-Moya, Miguel, Ballester, Patricia, Álvarez-Buylla, Elena R, Ferrándiz, Cristina
Format: Article
Language:English
Subjects:
Arabidopsis
Arabidopsis thaliana
Boolean
Boolean modeling
Dehiscence
Environmental aspects
fruit
Fruits
Genes
Genetic aspects
GRN
Growth
Identification and classification
Morphogenesis
Ovaries
Pericarp
Physiological aspects
Seed dispersal
Seeds
systems biology
Transcription factors
Valves
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Different convergent evolutionary strategies adopted by angiosperm fruits lead to diverse functional seed dispersal units. Dry dehiscent fruits are a common type of fruit, characterized by their lack of fleshy pericarp and the release of seeds at maturity through openings (dehiscence zones, DZs) in their structure. In previous decades, a set of core players in DZ formation have been intensively characterized in Arabidopsis and integrated in a gene regulatory network (GRN) that explains the morphogenesis of these tissues. In this work, we compile all the experimental data available to date to build a discrete Boolean model as a mechanistic approach to validate the network and, if needed, to identify missing components of the GRN and/or propose new hypothetical regulatory interactions, but also to provide a new formal framework to feed further work in Brassicaceae fruit development and the evolution of seed dispersal mechanisms. Hence, by means of exhaustive in-silico validations and experimental evidence, we are able to incorporate both the NO TRANSMITTING TRACT (NTT) transcription factor as a new additional node, and a new set of regulatory hypothetical rules to uncover the dynamics of Arabidopsis DZ specification.
ISSN:2223-7747
2223-7747
DOI:10.3390/plants13202927