Local hemostatic biomaterial based on native collagen

The article presents the results of obtaining a neutral biomaterial in the form of a sponge based on the aqueous mass of collagen isolated from the hide of cattle while maintaining the original fibrous structure. It has been established that at a concentration of water mass of collagen of 5-6%, a hi...

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Bibliographic Details
Published in:E3S web of conferences 2023-01, Vol.420, p.9004
Main Authors: Radjabov, O.I., Otajonov, A.Y., Baratov, K.R., Azimova, L.B.
Format: Article
Language:English
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Summary:The article presents the results of obtaining a neutral biomaterial in the form of a sponge based on the aqueous mass of collagen isolated from the hide of cattle while maintaining the original fibrous structure. It has been established that at a concentration of water mass of collagen of 5-6%, a high porosity of the biomaterial is observed. With an increase in the porosity of the biomaterial, its sorption capacity increases. It is shown that the biomaterial “Hemogubka” with a porosity of 87% has a pronounced hemostatic effect in rabbits with increased bleeding, and also reduces the time of parenchymal bleeding of the liver, kidneys, and spleen in rabbits by 48-73%, respectively, and is superior in efficiency to the action of a hemostatic sponge and hemostatic gauze 1.2-1.5 times.
ISSN:2267-1242
2267-1242
DOI:10.1051/e3sconf/202342009004