Angiotensin Converting Enzyme (ACE): A Marker for Personalized Feedback on Dieting

Angiotensin Converting Enzyme (ACE) expression and activity is associated with obesity. ACE is a circulating factor that predicts sustained weight loss over a time frame of months. Here, we evaluate whether ACE might also be an early marker (over a 24-hour period) for weight loss. 32 participants (7...

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Bibliographic Details
Published in:Nutrients 2020-02, Vol.12 (3), p.660
Main Authors: Tejpal, Shilpa, Sanghera, Narinder, Manoharan, Vijayalaxmi, Planas-Iglesias, Joan, Bastie, Claire C, Klein-Seetharaman, Judith
Format: Article
Language:English
Subjects:
ace
Angiotensin
Biofeedback
Biomarkers
Biomarkers - metabolism
Blood pressure
Body Mass Index
Body weight loss
Conversion
Correlation analysis
Diaries
Diet
dieting
Enzymes
Feedback
Food
Food intake
Humans
Insulin
Insulin - metabolism
Intervention
Lactic Acid - metabolism
Life Style
Markers
Metabolism
Metabolites
NMR
Nuclear magnetic resonance
Obesity
Peptidyl-dipeptidase A
Peptidyl-Dipeptidase A - metabolism
personalized feedback
Physical activity
Urine
Weight control
Weight Loss
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Summary:Angiotensin Converting Enzyme (ACE) expression and activity is associated with obesity. ACE is a circulating factor that predicts sustained weight loss over a time frame of months. Here, we evaluate whether ACE might also be an early marker (over a 24-hour period) for weight loss. 32 participants (78% females; BMI 28.47 ± 4.87kg/m2) followed a 1200KCal diet with an optional daily ( 25 ( ). This study demonstrated that ACE levels correlate with BMI and weight loss as early as after 1 day of dieting, and thus ACE could be a potential early "biofeedback" marker for weight loss and diet efficiency.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu12030660