Neurocognitive Profiles of Caucasian Moyamoya Disease Patients in Greece: A Case Series

The impact of Moyamoya Disease (MMD) on cognition inadult Caucasian patients has not yet been thoroughly investigated. The current study is the first to present detailed neuropsychological data on a series of Greek patients with MMD. A group of eight patients was assessed with an extensive neuropsyc...

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Published in:NeuroSci 2022-03, Vol.3 (1), p.119-129
Main Authors: Papageorgiou, Georgios, Kasselimis, Dimitrios, Angelopoulou, Georgia, Tsolakopoulos, Dimitrios, Laskaris, Nikolaos, Tountopoulou, Argyro, Korompoki, Eleni, Velonakis, Georgios, Chatziioannou, Achilles, Spengos, Konstantinos, Potagas, Constantin, Vassilopoulou, Sophia
Format: Article
Language:English
Subjects:
executive functions
moyamoya
social cognition
stroke
working memory
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Summary:The impact of Moyamoya Disease (MMD) on cognition inadult Caucasian patients has not yet been thoroughly investigated. The current study is the first to present detailed neuropsychological data on a series of Greek patients with MMD. A group of eight patients was assessed with an extensive neuropsychological battery, including measures of episodic memory, working memory, executive functions, language, and social cognition. The results indicated that MMD may be characterized by a trichotomous neurocognitive profile, characterized by prominent impairment in working memory, executive functions, and social cognition. Overall, we stress the need for a thorough cognitive evaluation of MMD patients and further highlight the potential importance of social cognition in this particular disease. Possible associations between the three impaired cognitive domains in our group are also discussed.
ISSN:2673-4087
2673-4087
DOI:10.3390/neurosci3010010