Comparison of the clinical characteristics and comprehensive assessments of the 2011 and 2017 GOLD classifications for patients with COPD in China

• Published in: International journal of chronic obstructive pulmonary disease 2018-01, Vol.13, p.3011-3019
• Main Authors: Hu, Yu-He, Liang, Zhen-Yu, Xu, Li-Mei, Xu, Wen-Hui, Liao, Hao, Li, Rui, Wang, Kai, Xu, Ying, Ou, Chun-Quan, Chen, Xin
• Format: Article
• Language: English
• Subjects: Administration, Inhalation; Adrenal Cortex Hormones - administration & dosage; Aerosols; Age Factors; Aged; Anxiety; Body Mass Index; Bronchodilator Agents - administration & dosage; China; Chronic obstructive lung disease; Chronic obstructive pulmonary disease; Classification; Comprehensive assessment; Cross-Sectional Studies; Data collection; Depression (Mood disorder); Dyspnea - physiopathology; Exercise Tolerance - physiology; Female; Future predictions; Global Initiative for Chronic Obstructive Lung Disease; Hospitals; Humans; Lung diseases; Male; Medical prognosis; Medical research; Middle Aged; Muscle function; Muscle strength; Nutritional status; Original Research; Oxygen saturation; Patients; Prognosis; Pulmonary Disease, Chronic Obstructive - classification; Pulmonary Disease, Chronic Obstructive - diagnosis; Pulmonary Disease, Chronic Obstructive - drug therapy; Pulmonary function tests; Quality of life; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Sex Factors; Smoking - adverse effects; Surveys
• ISSN: 1178-2005; 1176-9106; 1178-2005
• DOI: 10.2147/COPD.S174668

Compared with the 2011 Global Initiative for Chronic Obstructive Lung Disease (GOLD), there have been significant changes in the 2017 GOLD classification. The purpose of this study was to analyze the changes in clinical characteristics of the new A-B-C-D system and to explore its role in comprehensive assessment of COPD. A total of 631 stable COPD patients were included in a cross-sectional survey. Data collected included baseline data and pulmonary function testing results, respiratory muscle strength, symptoms and quality of life, exercise capacity, nutritional status, and anxiety and depression as a comprehensive assessment. Based on the 2011 GOLD and 2017 GOLD classifications, patients were divided into Groups A -D and Groups A -D , respectively. In the 2011 GOLD, 64 subjects in Group C were reclassified into Group A (41.6%), while 77 subjects in Group D were reclassified into Group B (27.1%). The old and new grading systems were somewhat consistent (Cohen's kappa=0.6963,