The Significance of Dual-Energy X-ray Absorptiometry (DXA) Examination in Cushing's Syndrome-A Systematic Review

In recent years, the usefulness of dual-energy X-ray absorptiometry (DXA) as a valuable complementary method of assessing the content and distribution of adipose and lean tissue as well as bone mineral density and estimating the risk of fractures has been increasingly confirmed. The diagnosis and tr...

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Bibliographic Details
Published in:Diagnostics (Basel) 2023-04, Vol.13 (9), p.1576
Main Authors: Radecka, Aleksandra, Lubkowska, Anna
Format: Article
Language:English
Subjects:
ALMI—appendicular lean mass index
BMD—bone mineral density
Body composition
Body fat
Bones
Care and treatment
Cushing’s syndrome
Density
dual-energy X-ray absorptiometry
Energy
FMI—fat mass index
Fractures
Gastrointestinal surgery
Metabolism
NMR
Nuclear magnetic resonance
Osteoporosis
Radiation
Risk factors
Systematic Review
Tomography
VFA—vertebral fracture assessment
X-rays
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Summary:In recent years, the usefulness of dual-energy X-ray absorptiometry (DXA) as a valuable complementary method of assessing the content and distribution of adipose and lean tissue as well as bone mineral density and estimating the risk of fractures has been increasingly confirmed. The diagnosis and treatment of Cushing's syndrome remain challenging, and monitoring the effects of treatment is often necessary. DXA tests offer a potential solution to many problems related to the availability of a quick, detailed, and reliable analysis of changes in the content and distribution of individual body composition components. The article discusses total body DXA scans (FMI, VAT, ALMI), lumbar spine scans (VFA, TBS), and osteoporosis scans (BMD, T-score, Z-score)-all are of potential interest in Cushing's syndrome. The article discusses the use of the most important indicators obtained from a DXA test (FMI, VAT, ALMI, BMD, T-score, Z-score, VFA, TBS) and their clinical significance in Cushing's syndrome was verified. The literature from the last decade was used for the study, available in MEDLINE, Web of Science, and ScienceDirect.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics13091576