COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON

Currently, the market offers a wide variety of suture threads, made of materials with different structural and chemical properties. Among many other characteristics, they vary in origin, absorption or degradation, and structure. From this variety, the clinical doubt arises as to which material provi...

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Bibliographic Details
Published in:Acta ortopedica brasileira 2023-01, Vol.31 (4), p.e266635-e266635
Main Authors: Alves, Rafael Saleme, Tanaka, Leonardo Yabu, Carvalho, Victor Bignatto, Lopes, Leticia Candido, Santos, Sofia Brandão Dos, Dsouki, Nuha Ahmad, Pereira, Bruno Fiorelini, Sato, Monica Akemi
Format: Article
Language:English
Subjects:
Inflammation
Metalloproteinases
Original
ORTHOPEDICS
Skin
Sutures
Tissue Inhibitor of Metalloproteinases
Wound Healing
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Summary:Currently, the market offers a wide variety of suture threads, made of materials with different structural and chemical properties. Among many other characteristics, they vary in origin, absorption or degradation, and structure. From this variety, the clinical doubt arises as to which material provides the patient with the best healing quality. This study aims to comparatively evaluate two different types of suture threads-Monocryl (polyglycaprone 25) and Ethilon (nylon)-regarding their ability to aid in tissue regeneration by a histological and immunohistochemical analysis of the skin of rats sutured with the aforementioned materials. This basic experimental study used 12 adult Wistar rats, randomly divided into three groups with four animals each and subjected to four longitudinal incisions under anesthesia. Each group corresponded to a postsurgical evaluation date (one, seven, and 14 days). At 14 postoperative days, the studied groups had no histological difference. However, the use of nylon thread showed greater evidence of earlier fibrotic union. This study found no histological difference in healing 14 days after surgery among the techniques and the types of suture threads.
ISSN:1413-7852
1809-4406
1809-4406
DOI:10.1590/1413-785220233104e266635