Semen characteristics of individuals before and after Covishield™ vaccination

Concern about fertility impairment after vaccination is one of the reasons for vaccine hesitancy in the population. This retrospective observational study aims to understand the impact of Covishield™ (ChAdOx1 nCoV-19 corona virus vaccine, recombinant) COVID-19 vaccination on ejaculate quality in 53...

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Bibliographic Details
Published in:Reproduction & fertility 2022-07, Vol.3 (3), p.216-219
Main Authors: Meitei, Huidrom Yaiphaba, Uppangala, Shubhashree, Lakshmi R, Vani, Kalthur, Guruprasad, Adiga, Satish Kumar
Format: Article
Language:English
Subjects:
covid-19 vaccination
covishield
male infertility
semen quality
sperm
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Summary:Concern about fertility impairment after vaccination is one of the reasons for vaccine hesitancy in the population. This retrospective observational study aims to understand the impact of Covishield™ (ChAdOx1 nCoV-19 corona virus vaccine, recombinant) COVID-19 vaccination on ejaculate quality in 53 patients undergoing semen analysis between 2018 and 2021. A baseline semen profile was recorded from the subjects during their visit before the vaccination for fertility work-up. Follow-up ejaculates were provided approximately 82 (Q1: 37, Q3: 124) days after the second dose of vaccination. Semen characteristics such as volume, sperm concentration, sperm motility, and morphological abnormalities were recorded. Of the 53 subjects, 33 (62%) had semen characteristics above the World Health Organization (WHO) reference. In general, no significant variations in the semen parameters were observed except for a moderate decline in sperm morphology ( P  
ISSN:2633-8386
2633-8386
DOI:10.1530/RAF-22-0046