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Atypical skull-base osteomyelitis: Comprehensive review and multidisciplinary management viewpoints

Atypical skull-base osteomyelitis is a rare but fatal disease that usually involves infection of the ethmoid, sphenoid, occipital, or temporal bones that form the skull base. Unlike typical (so-called otogenic), atypical skull-base osteomyelitis has no otogenic cause. Instead, some authors call atyp...

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Published in:Tropical medicine and infectious disease 2023-04, Vol.8 (5), p.1-19
Main Authors: Urbančič, Jure, Vozel, Domen, Battelino, Saba, Bošnjak, Roman, Kokošar Ulčar, Barbara, Matos, Tadeja, Munda, Matic, Papst, Lea, Steiner, Nejc, Vouk, Matej, Zidar, Nina
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Language:English
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Summary:Atypical skull-base osteomyelitis is a rare but fatal disease that usually involves infection of the ethmoid, sphenoid, occipital, or temporal bones that form the skull base. Unlike typical (so-called otogenic), atypical skull-base osteomyelitis has no otogenic cause. Instead, some authors call atypical skull-base osteomyelitis sinonasal, since the infection most often originates from the nose and paranasal sinuses. Diagnosing and treating this disease is challenging. To assist in managing atypical skull-base osteomyelitis, a review of the most recent literature, with patient cases and multidisciplinary perspectives from otolaryngologists, neurosurgeons, radiologists, infectious disease specialists, pathologists, and clinical microbiologists, is provided in this paper.
ISSN:2414-6366
2414-6366
DOI:10.3390/tropicalmed8050254