Ion-Doped Calcium Phosphate-Based Coatings with Antibacterial Properties

Ion-substituted calcium phosphate (CP) coatings have been extensively studied as promising materials for biomedical implants due to their ability to enhance biocompatibility, osteoconductivity, and bone formation. This systematic review aims to provide a comprehensive analysis of the current state o...

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Bibliographic Details
Published in:Journal of functional biomaterials 2023-04, Vol.14 (5), p.250
Main Authors: Fosca, Marco, Streza, Alexandru, Antoniac, Iulian V, Vadalà, Gianluca, Rau, Julietta V
Format: Article
Language:English
Subjects:
Analysis
antibacterial
Antibacterial agents
Antibacterial materials
Bacteria
Biocompatibility
Biological properties
Biomedical materials
Bone growth
bone implant
Bone implants
Calcium phosphate
Calcium phosphates
coating
Coatings
Dental implants
Dental materials
Dental prosthetics
Dental restorative materials
Enzymes
Gram-negative bacteria
Gram-positive bacteria
Hydroxyapatite
Implant dentures
Infections
ion-doped
ion-substituted
Ions
Mechanical properties
Microscopy
Morphology
Orthopedics
Osteoconduction
Osteogenesis
Oxidative stress
Protein synthesis
Review
Reviews
Surgical implants
Transplants & implants
Wound healing
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Description
Summary:Ion-substituted calcium phosphate (CP) coatings have been extensively studied as promising materials for biomedical implants due to their ability to enhance biocompatibility, osteoconductivity, and bone formation. This systematic review aims to provide a comprehensive analysis of the current state of the art in ion-doped CP-based coatings for orthopaedic and dental implant applications. Specifically, this review evaluates the effects of ion addition on the physicochemical, mechanical, and biological properties of CP coatings. The review also identifies the contribution and additional effects (in a separate or a synergistic way) of different components used together with ion-doped CP for advanced composite coatings. In the final part, the effects of antibacterial coatings on specific bacteria strains are reported. The present review could be of interest to researchers, clinicians, and industry professionals involved in the development and application of CP coatings for orthopaedic and dental implants.
ISSN:2079-4983
2079-4983
DOI:10.3390/jfb14050250