Loading…
Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge
SARS-CoV-2 infection has raised concerns about long-term health repercussions. Exercise ventilatory inefficiency (EVin) has emerged as a notable long-term sequela, potentially impacting respiratory and cardiovascular health. This study aims to assess the long-term presence of EVin after 34 months an...
Saved in:
| Published in: | BMC pulmonary medicine 2024-05, Vol.24 (1), p.258-258, Article 258 |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | cdi_FETCH-LOGICAL-c445t-70a7a3af684d0bc7f24b3cfcd50b022000da435987affc8ff427b9660846bfb3 |
| container_end_page | 258 |
| container_issue | 1 |
| container_start_page | 258 |
| container_title | BMC pulmonary medicine |
| container_volume | 24 |
| creator | Dorelli, Gianluigi Sartori, Giulia Fasoli, Giulia Ridella, Nicolò Bianchini, Nicola Braggio, Michele Ferrari, Marcello Venturelli, Massimo Carbonare, Luca Dalle Capelli, Carlo Grassi, Bruno Crisafulli, Ernesto |
| description | SARS-CoV-2 infection has raised concerns about long-term health repercussions. Exercise ventilatory inefficiency (EVin) has emerged as a notable long-term sequela, potentially impacting respiratory and cardiovascular health. This study aims to assess the long-term presence of EVin after 34 months and its association with cardiorespiratory health in post-COVID patients.
In a longitudinal study on 32 selected post-COVID subjects, we performed two cardiopulmonary exercise tests (CPETs) at 6 months (T0) and 34 months (T1) after hospital discharge. The study sought to explore the long-term persistence of EVin and its correlation with respiratory and cardiovascular responses during exercise. Measurements included also V̇O
end-tidal pressure of CO
(PET
) levels, oxygen uptake efficiency slope (OUES) and other cardiorespiratory parameters, with statistical significance set at p |
| doi_str_mv | 10.1186/s12890-024-03070-1 |
| format | article |
| fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_91aa83d378214936aaa210bba1c16e14</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A795328715</galeid><doaj_id>oai_doaj_org_article_91aa83d378214936aaa210bba1c16e14</doaj_id><sourcerecordid>A795328715</sourcerecordid><originalsourceid>FETCH-LOGICAL-c445t-70a7a3af684d0bc7f24b3cfcd50b022000da435987affc8ff427b9660846bfb3</originalsourceid><addsrcrecordid>eNptUk2P0zAQjRCIXRb-AAdkiQuXFH_Fdk5oVb4qVVoOK67WxLFTV0lc7KRi_wC_G7ddli1CPng8fu-NZ_yK4jXBC0KUeJ8IVTUuMeUlZljikjwpLgmXpKRciKeP4oviRUpbjIlUFXteXDAla8EZvSx-fbMx-TT5sUP2p43GJ4v2dpx8D1OId8iP1jlvvB3N4YDS3GytmRKK1oS9jQeii2FAy5vvq48lqRdoHcbOT3PrR-hRCxMgyNFdLoMYR0MYp01Cu5CmsvXJbCB29mXxzEGf7Kv7_aq4_fzpdvm1XN98WS2v16XhvJpKiUECAycUb3FjpKO8YcaZtsINphRj3AJnVa0kOGeUc5zKphYCKy4a17CrYnWSbQNs9S76AeKdDuD1MRFipyFO3vRW1wRAsZZJRQmvmQAASnDTADFEWMKz1oeT1m5uBtuaPLMI_Zno-c3oN7oLe01I_jeCaVZ4d68Qw4_ZpkkPeR6272G0YU6aYYEllxUhGfr2H-g2zDFP9YgSSlW4on9RHeQO_OhCLmwOovpa1hWjSpIqoxb_QeXV2sGbkP_b5_wZgZ4IJoaUonUPTRKsD07UJyfq7ER9dKI-vPjN4_E8UP5Yj_0GdgLZrQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3066885052</pqid></control><display><type>article</type><title>Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge</title><source>Open Access: PubMed Central</source><source>Publicly Available Content Database</source><source>Coronavirus Research Database</source><creator>Dorelli, Gianluigi ; Sartori, Giulia ; Fasoli, Giulia ; Ridella, Nicolò ; Bianchini, Nicola ; Braggio, Michele ; Ferrari, Marcello ; Venturelli, Massimo ; Carbonare, Luca Dalle ; Capelli, Carlo ; Grassi, Bruno ; Crisafulli, Ernesto</creator><creatorcontrib>Dorelli, Gianluigi ; Sartori, Giulia ; Fasoli, Giulia ; Ridella, Nicolò ; Bianchini, Nicola ; Braggio, Michele ; Ferrari, Marcello ; Venturelli, Massimo ; Carbonare, Luca Dalle ; Capelli, Carlo ; Grassi, Bruno ; Crisafulli, Ernesto</creatorcontrib><description>SARS-CoV-2 infection has raised concerns about long-term health repercussions. Exercise ventilatory inefficiency (EVin) has emerged as a notable long-term sequela, potentially impacting respiratory and cardiovascular health. This study aims to assess the long-term presence of EVin after 34 months and its association with cardiorespiratory health in post-COVID patients.
In a longitudinal study on 32 selected post-COVID subjects, we performed two cardiopulmonary exercise tests (CPETs) at 6 months (T0) and 34 months (T1) after hospital discharge. The study sought to explore the long-term persistence of EVin and its correlation with respiratory and cardiovascular responses during exercise. Measurements included also V̇O
end-tidal pressure of CO
(PET
) levels, oxygen uptake efficiency slope (OUES) and other cardiorespiratory parameters, with statistical significance set at p < 0.05. The presence of EVin at both T0 and T1 defines a persisting EVin (pEVin).
Out of the cohort, five subjects (16%) have pEVin at 34 months. Subjects with pEVin, compared to those with ventilatory efficiency (Evef) have lower values of PET
throughout exercise, showing hyperventilation. Evef subjects demonstrated selective improvements in DL
and oxygen pulse, suggesting a recovery in cardiorespiratory function over time. In contrast, those with pEvin did not exhibit these improvements. Notably, significant correlations were found between hyperventilation (measured by PET
), oxygen pulse and OUES, indicating the potential prognostic value of OUES and Evin in post-COVID follow-ups.
The study highlights the clinical importance of long-term follow-up for post-COVID patients, as a significant group exhibit persistent EVin, which correlates with altered and potentially unfavorable cardiovascular responses to exercise. These findings advocate for the continued investigation into the long-term health impacts of COVID-19, especially regarding persistent ventilatory inefficiencies and their implications on patient health outcomes.</description><identifier>ISSN: 1471-2466</identifier><identifier>EISSN: 1471-2466</identifier><identifier>DOI: 10.1186/s12890-024-03070-1</identifier><identifier>PMID: 38796432</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Aged ; Analysis ; Artificial respiration ; Asymptomatic ; Blood pressure ; Carbon dioxide ; Cardiopulmonary exercise test ; Cardiovascular system ; Chronic illnesses ; COVID-19 ; COVID-19 - complications ; COVID-19 - physiopathology ; Data analysis ; Efficiency ; Electrocardiography ; End-tidal pressure of CO2 ; Exercise ; Exercise - physiology ; Exercise Test ; Exercise tests ; Exercise ventilatory inefficiency ; Female ; Humans ; Hypertension ; Hyperventilation ; Hypotheses ; Infections ; Longitudinal Studies ; Male ; Middle Aged ; Oxygen Consumption - physiology ; Oxygen pulse ; Patient Discharge ; Patient outcomes ; Patients ; Physical fitness ; Physiology, Pathological ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2</subject><ispartof>BMC pulmonary medicine, 2024-05, Vol.24 (1), p.258-258, Article 258</ispartof><rights>2024. The Author(s).</rights><rights>COPYRIGHT 2024 BioMed Central Ltd.</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c445t-70a7a3af684d0bc7f24b3cfcd50b022000da435987affc8ff427b9660846bfb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11128102/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3066885052?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25733,27903,27904,36991,36992,38495,43874,44569,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38796432$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dorelli, Gianluigi</creatorcontrib><creatorcontrib>Sartori, Giulia</creatorcontrib><creatorcontrib>Fasoli, Giulia</creatorcontrib><creatorcontrib>Ridella, Nicolò</creatorcontrib><creatorcontrib>Bianchini, Nicola</creatorcontrib><creatorcontrib>Braggio, Michele</creatorcontrib><creatorcontrib>Ferrari, Marcello</creatorcontrib><creatorcontrib>Venturelli, Massimo</creatorcontrib><creatorcontrib>Carbonare, Luca Dalle</creatorcontrib><creatorcontrib>Capelli, Carlo</creatorcontrib><creatorcontrib>Grassi, Bruno</creatorcontrib><creatorcontrib>Crisafulli, Ernesto</creatorcontrib><title>Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge</title><title>BMC pulmonary medicine</title><addtitle>BMC Pulm Med</addtitle><description>SARS-CoV-2 infection has raised concerns about long-term health repercussions. Exercise ventilatory inefficiency (EVin) has emerged as a notable long-term sequela, potentially impacting respiratory and cardiovascular health. This study aims to assess the long-term presence of EVin after 34 months and its association with cardiorespiratory health in post-COVID patients.
In a longitudinal study on 32 selected post-COVID subjects, we performed two cardiopulmonary exercise tests (CPETs) at 6 months (T0) and 34 months (T1) after hospital discharge. The study sought to explore the long-term persistence of EVin and its correlation with respiratory and cardiovascular responses during exercise. Measurements included also V̇O
end-tidal pressure of CO
(PET
) levels, oxygen uptake efficiency slope (OUES) and other cardiorespiratory parameters, with statistical significance set at p < 0.05. The presence of EVin at both T0 and T1 defines a persisting EVin (pEVin).
Out of the cohort, five subjects (16%) have pEVin at 34 months. Subjects with pEVin, compared to those with ventilatory efficiency (Evef) have lower values of PET
throughout exercise, showing hyperventilation. Evef subjects demonstrated selective improvements in DL
and oxygen pulse, suggesting a recovery in cardiorespiratory function over time. In contrast, those with pEvin did not exhibit these improvements. Notably, significant correlations were found between hyperventilation (measured by PET
), oxygen pulse and OUES, indicating the potential prognostic value of OUES and Evin in post-COVID follow-ups.
The study highlights the clinical importance of long-term follow-up for post-COVID patients, as a significant group exhibit persistent EVin, which correlates with altered and potentially unfavorable cardiovascular responses to exercise. These findings advocate for the continued investigation into the long-term health impacts of COVID-19, especially regarding persistent ventilatory inefficiencies and their implications on patient health outcomes.</description><subject>Adult</subject><subject>Aged</subject><subject>Analysis</subject><subject>Artificial respiration</subject><subject>Asymptomatic</subject><subject>Blood pressure</subject><subject>Carbon dioxide</subject><subject>Cardiopulmonary exercise test</subject><subject>Cardiovascular system</subject><subject>Chronic illnesses</subject><subject>COVID-19</subject><subject>COVID-19 - complications</subject><subject>COVID-19 - physiopathology</subject><subject>Data analysis</subject><subject>Efficiency</subject><subject>Electrocardiography</subject><subject>End-tidal pressure of CO2</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Exercise Test</subject><subject>Exercise tests</subject><subject>Exercise ventilatory inefficiency</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hyperventilation</subject><subject>Hypotheses</subject><subject>Infections</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Oxygen Consumption - physiology</subject><subject>Oxygen pulse</subject><subject>Patient Discharge</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Physical fitness</subject><subject>Physiology, Pathological</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><issn>1471-2466</issn><issn>1471-2466</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUk2P0zAQjRCIXRb-AAdkiQuXFH_Fdk5oVb4qVVoOK67WxLFTV0lc7KRi_wC_G7ddli1CPng8fu-NZ_yK4jXBC0KUeJ8IVTUuMeUlZljikjwpLgmXpKRciKeP4oviRUpbjIlUFXteXDAla8EZvSx-fbMx-TT5sUP2p43GJ4v2dpx8D1OId8iP1jlvvB3N4YDS3GytmRKK1oS9jQeii2FAy5vvq48lqRdoHcbOT3PrR-hRCxMgyNFdLoMYR0MYp01Cu5CmsvXJbCB29mXxzEGf7Kv7_aq4_fzpdvm1XN98WS2v16XhvJpKiUECAycUb3FjpKO8YcaZtsINphRj3AJnVa0kOGeUc5zKphYCKy4a17CrYnWSbQNs9S76AeKdDuD1MRFipyFO3vRW1wRAsZZJRQmvmQAASnDTADFEWMKz1oeT1m5uBtuaPLMI_Zno-c3oN7oLe01I_jeCaVZ4d68Qw4_ZpkkPeR6272G0YU6aYYEllxUhGfr2H-g2zDFP9YgSSlW4on9RHeQO_OhCLmwOovpa1hWjSpIqoxb_QeXV2sGbkP_b5_wZgZ4IJoaUonUPTRKsD07UJyfq7ER9dKI-vPjN4_E8UP5Yj_0GdgLZrQ</recordid><startdate>20240525</startdate><enddate>20240525</enddate><creator>Dorelli, Gianluigi</creator><creator>Sartori, Giulia</creator><creator>Fasoli, Giulia</creator><creator>Ridella, Nicolò</creator><creator>Bianchini, Nicola</creator><creator>Braggio, Michele</creator><creator>Ferrari, Marcello</creator><creator>Venturelli, Massimo</creator><creator>Carbonare, Luca Dalle</creator><creator>Capelli, Carlo</creator><creator>Grassi, Bruno</creator><creator>Crisafulli, Ernesto</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240525</creationdate><title>Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge</title><author>Dorelli, Gianluigi ; Sartori, Giulia ; Fasoli, Giulia ; Ridella, Nicolò ; Bianchini, Nicola ; Braggio, Michele ; Ferrari, Marcello ; Venturelli, Massimo ; Carbonare, Luca Dalle ; Capelli, Carlo ; Grassi, Bruno ; Crisafulli, Ernesto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-70a7a3af684d0bc7f24b3cfcd50b022000da435987affc8ff427b9660846bfb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Analysis</topic><topic>Artificial respiration</topic><topic>Asymptomatic</topic><topic>Blood pressure</topic><topic>Carbon dioxide</topic><topic>Cardiopulmonary exercise test</topic><topic>Cardiovascular system</topic><topic>Chronic illnesses</topic><topic>COVID-19</topic><topic>COVID-19 - complications</topic><topic>COVID-19 - physiopathology</topic><topic>Data analysis</topic><topic>Efficiency</topic><topic>Electrocardiography</topic><topic>End-tidal pressure of CO2</topic><topic>Exercise</topic><topic>Exercise - physiology</topic><topic>Exercise Test</topic><topic>Exercise tests</topic><topic>Exercise ventilatory inefficiency</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hyperventilation</topic><topic>Hypotheses</topic><topic>Infections</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Oxygen Consumption - physiology</topic><topic>Oxygen pulse</topic><topic>Patient Discharge</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Physical fitness</topic><topic>Physiology, Pathological</topic><topic>SARS-CoV-2</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dorelli, Gianluigi</creatorcontrib><creatorcontrib>Sartori, Giulia</creatorcontrib><creatorcontrib>Fasoli, Giulia</creatorcontrib><creatorcontrib>Ridella, Nicolò</creatorcontrib><creatorcontrib>Bianchini, Nicola</creatorcontrib><creatorcontrib>Braggio, Michele</creatorcontrib><creatorcontrib>Ferrari, Marcello</creatorcontrib><creatorcontrib>Venturelli, Massimo</creatorcontrib><creatorcontrib>Carbonare, Luca Dalle</creatorcontrib><creatorcontrib>Capelli, Carlo</creatorcontrib><creatorcontrib>Grassi, Bruno</creatorcontrib><creatorcontrib>Crisafulli, Ernesto</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>BMC pulmonary medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dorelli, Gianluigi</au><au>Sartori, Giulia</au><au>Fasoli, Giulia</au><au>Ridella, Nicolò</au><au>Bianchini, Nicola</au><au>Braggio, Michele</au><au>Ferrari, Marcello</au><au>Venturelli, Massimo</au><au>Carbonare, Luca Dalle</au><au>Capelli, Carlo</au><au>Grassi, Bruno</au><au>Crisafulli, Ernesto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge</atitle><jtitle>BMC pulmonary medicine</jtitle><addtitle>BMC Pulm Med</addtitle><date>2024-05-25</date><risdate>2024</risdate><volume>24</volume><issue>1</issue><spage>258</spage><epage>258</epage><pages>258-258</pages><artnum>258</artnum><issn>1471-2466</issn><eissn>1471-2466</eissn><abstract>SARS-CoV-2 infection has raised concerns about long-term health repercussions. Exercise ventilatory inefficiency (EVin) has emerged as a notable long-term sequela, potentially impacting respiratory and cardiovascular health. This study aims to assess the long-term presence of EVin after 34 months and its association with cardiorespiratory health in post-COVID patients.
In a longitudinal study on 32 selected post-COVID subjects, we performed two cardiopulmonary exercise tests (CPETs) at 6 months (T0) and 34 months (T1) after hospital discharge. The study sought to explore the long-term persistence of EVin and its correlation with respiratory and cardiovascular responses during exercise. Measurements included also V̇O
end-tidal pressure of CO
(PET
) levels, oxygen uptake efficiency slope (OUES) and other cardiorespiratory parameters, with statistical significance set at p < 0.05. The presence of EVin at both T0 and T1 defines a persisting EVin (pEVin).
Out of the cohort, five subjects (16%) have pEVin at 34 months. Subjects with pEVin, compared to those with ventilatory efficiency (Evef) have lower values of PET
throughout exercise, showing hyperventilation. Evef subjects demonstrated selective improvements in DL
and oxygen pulse, suggesting a recovery in cardiorespiratory function over time. In contrast, those with pEvin did not exhibit these improvements. Notably, significant correlations were found between hyperventilation (measured by PET
), oxygen pulse and OUES, indicating the potential prognostic value of OUES and Evin in post-COVID follow-ups.
The study highlights the clinical importance of long-term follow-up for post-COVID patients, as a significant group exhibit persistent EVin, which correlates with altered and potentially unfavorable cardiovascular responses to exercise. These findings advocate for the continued investigation into the long-term health impacts of COVID-19, especially regarding persistent ventilatory inefficiencies and their implications on patient health outcomes.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38796432</pmid><doi>10.1186/s12890-024-03070-1</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1471-2466 |
| ispartof | BMC pulmonary medicine, 2024-05, Vol.24 (1), p.258-258, Article 258 |
| issn | 1471-2466 1471-2466 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_91aa83d378214936aaa210bba1c16e14 |
| source | Open Access: PubMed Central; Publicly Available Content Database; Coronavirus Research Database |
| subjects | Adult Aged Analysis Artificial respiration Asymptomatic Blood pressure Carbon dioxide Cardiopulmonary exercise test Cardiovascular system Chronic illnesses COVID-19 COVID-19 - complications COVID-19 - physiopathology Data analysis Efficiency Electrocardiography End-tidal pressure of CO2 Exercise Exercise - physiology Exercise Test Exercise tests Exercise ventilatory inefficiency Female Humans Hypertension Hyperventilation Hypotheses Infections Longitudinal Studies Male Middle Aged Oxygen Consumption - physiology Oxygen pulse Patient Discharge Patient outcomes Patients Physical fitness Physiology, Pathological SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 |
| title | Persisting exercise ventilatory inefficiency in subjects recovering from COVID-19. Longitudinal data analysis 34 months post-discharge |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T16%3A26%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Persisting%20exercise%20ventilatory%20inefficiency%20in%20subjects%20recovering%20from%20COVID-19.%20Longitudinal%20data%20analysis%2034%20months%20post-discharge&rft.jtitle=BMC%20pulmonary%20medicine&rft.au=Dorelli,%20Gianluigi&rft.date=2024-05-25&rft.volume=24&rft.issue=1&rft.spage=258&rft.epage=258&rft.pages=258-258&rft.artnum=258&rft.issn=1471-2466&rft.eissn=1471-2466&rft_id=info:doi/10.1186/s12890-024-03070-1&rft_dat=%3Cgale_doaj_%3EA795328715%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c445t-70a7a3af684d0bc7f24b3cfcd50b022000da435987affc8ff427b9660846bfb3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3066885052&rft_id=info:pmid/38796432&rft_galeid=A795328715&rfr_iscdi=true |