Small cell carcinoma in ulcerative colitis--new treatment option: a case report

The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC. A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented...

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Bibliographic Details
Published in:World journal of surgical oncology 2010-11, Vol.8 (1), p.100-100, Article 100
Main Authors: Kosmidis, Christoforos, Efthimiadis, Christoforos, Anthimidis, Georgios, Vasiliadou, Kalliopi, Tzeveleki, Ioanna, Fotiadis, Panagiotis, Basdanis, Georgios
Format: Article
Language:English
Subjects:
Adenocarcinoma - etiology
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Care and treatment
Case Report
Case studies
Colitis, Ulcerative - pathology
Colitis, Ulcerative - surgery
Colon (Anatomy)
Colonic Pouches
Colonoscopy
Colorectal cancer
Complications and side effects
Development and progression
Humans
Magnetic Resonance Imaging
Male
Proctocolectomy, Restorative
Prognosis
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
Small Cell Lung Carcinoma - pathology
Small Cell Lung Carcinoma - surgery
Surgery
Ulcerative colitis
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Summary:The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC. A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented with mucoid-bloody diarrhea. Colonoscopy revealed a rectal mass 2 cm distant from the anal verge. The patient underwent a total proctocolectomy with preservation of the anal sphincters, construction of an ileal reservoir, anastomosis of the reservoir to the anus (J configuration) and protective loop ileostomy. Histological examination showed undifferentiated small cell carcinoma. This is the first case of small cell carcinoma in a background of UC reported to be treated surgically and the patient and has no recurrence 18 months postoperatively.
ISSN:1477-7819
1477-7819
DOI:10.1186/1477-7819-8-100