Large-cell neuroendocrine carcinoma of the kidney: Clinicopathologic features

Neuroendocrine tumors are rare entities which can arise in various sites of the body. The presence of both neural and endocrine elements in conjunction characterises these tumors pathologically. Most of these tumors are non secretory in nature, and arise in organs where there may not be any neuroend...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of urology 2009-04, Vol.25 (2), p.274-275
Main Authors: Ratnagiri, Ranganath, Singh, Shirley Sunder, Majhi, Urmila, Kathiresan, Sateeshan
Format: Article
Language:English
Subjects:
Blood clots
Cancer
Care and treatment
Case studies
Diagnosis
Immuno histochemistry
Immunohistochemistry
kidney
Kidney cancer
neuroendocrine tumors
Patient outcomes
Risk factors
Tumors
Uropathology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Neuroendocrine tumors are rare entities which can arise in various sites of the body. The presence of both neural and endocrine elements in conjunction characterises these tumors pathologically. Most of these tumors are non secretory in nature, and arise in organs where there may not be any neuroendocrine elements. Carcinoid tumors are the most common entities reported in the kidney. There have been only a couple of case series of non-carcinoid neuroendocrine tumors of the kidney reported in literature. Surgical resection appears to be the best available treatment modality. Chemotherapy has been attempted with dismal results. The biological behaviour is determined by the occurrence of metastases to the liver or lung. We report a patient with a large cell neuroendocrine carcinoma of the kidney, who underwent radical resection and is doing well on follow-up. The diagnosis was confirmed by immune-histochemistry.
ISSN:0970-1591
1998-3824
DOI:10.4103/0970-1591.52928