Biophysical measurements and ultrasonographic findings in chronic dermatitis in comparison with uninvolved skin

Background: Nowadays noninvasive techniques are performed to evaluate the biophysical properties of skin in vivo. Aims: The aim of this study was to evaluate the biophysical and ultrasonographic properties of skin in chronic contact or atopic dermatitis to provide better insight into pathogenesis, d...

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Bibliographic Details
Published in:Indian journal of dermatology 2019-03, Vol.64 (2), p.90-96
Main Authors: Yazdanparast, Taraneh, Yazdani, Kamran, Humbert, Philippe, Khatami, Alireza, Nasrollahi, Saman, Firouzabadi, Leila, Firooz, Alireza
Format: Article
Language:English
Subjects:
Age
Analysis
Atopic dermatitis
Basic Research
Biomechanical properties
biophysical properties
chronic dermatitis
Comparative analysis
Dermatitis
Eczema
Erythema
Free radicals
Hydration
Inflammation
Patients
Physical properties
Physiological aspects
Skin
Skin diseases
Systemic diseases
Ultrasonic imaging
ultrasonography
Ultrasound imaging
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Summary:Background: Nowadays noninvasive techniques are performed to evaluate the biophysical properties of skin in vivo. Aims: The aim of this study was to evaluate the biophysical and ultrasonographic properties of skin in chronic contact or atopic dermatitis to provide better insight into pathogenesis, diagnosis, and treatment response. Materials and Methods: The stratum corneum hydration, transepidermal water loss (TEWL), pH, erythema, melanin, sebum, friction, temperature, elasticity parameters (R0, R2, and R5), the thickness and echo-density of epidermis, dermis, and subepidermal low-echogenic band (SLEB) were measured on lesional, perilesional, and symmetrical skin of 22 chronic dermatitis patients. The average of perilesional and symmetrical skin values (control) was compared with lesional values. Results: Stratum corneum hydration (P
ISSN:0019-5154
1998-3611
DOI:10.4103/ijd.IJD_464_17